Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder

NNJ Rommelse, B Franke, HM Geurts… - European child & …, 2010 - Springer
… studies [family based, twin, candidate gene, linkage, and … overlapping candidate genes and
genome-wide association findings for both … which likely represent genetic rather than shared …

Influence of CFH gene on symptom severity of schizophrenia

C Zhang, Q Lv, W Fan, W Tang, Z Yi - … disease and treatment, 2017 - Taylor & Francis
Family, twin and adoption studies have demonstrated that … Citation1 Recent genome-wide
association studies (GWASs) … Brain eQTL (expression quantitative trait loci) analysis for CFH …

A whole genome association study of neuroticism using DNA pooling

S Shifman, A Bhomra, S Smiley, NR Wray… - Molecular …, 2008 - nature.com
… by our laboratory and in a family-based test in an independent sample; … DNA pooling can
also be applied to quantitative traits in a … To estimate a genome-wide significance threshold, we …

Genetic risk for schizophrenia and psychosis in Alzheimer disease

MAA DeMichele-Sweet, EA Weamer, L Klei… - Molecular …, 2018 - nature.com
psychosis in a family member with AD, given the presence of … reported the first genome-wide
association study (GWAS) of … ) of cis-expression quantitative trait loci (cis-eQTLs) affecting …

[图书][B] Quantitative Trait Loci for Brain Morphology and Complex Behavior: Neurogenetics in Cognitive Neuroscience

RE Laughlin - 2010 - search.proquest.com
… a linkage disequilibrium was present using WebQTL as both a mapping engine and genomic
database. For neocortex, we found a genome-wide significant quantitative trait … gpl30 family

Anhedonia as an indicator of genetic vulnerability to schizophrenia

AR Docherty, SR Sponheim - Anhedonia: A Comprehensive Handbook …, 2014 - Springer
… to model genome-wide polygenic risk for symptom dimensions that make up … quantitative
trait need to be compatible with the presence of unequal family sizes and varying types of family

Genome-wide association study for autism spectrum disorder in Taiwanese Han population

PH Kuo, LC Chuang, MH Su, CH Chen, CH Chen… - PLoS …, 2015 - journals.plos.org
… We used the Illumina custom genotyping array with multiplex … ASD or autism related quantitative
traits (eg language delay) [… a Quebec family study revealed a significant linkage peak on …

Schizophrenia: a review of genetic studies

MT Tsuang, WS Stone, SV Faraone - Harvard Review of Psychiatry, 1999 - Taylor & Francis
… We begin with a review of family studies of schizophrenia, to … “Quantitative trait loci” is used
to refer to multiple genes … using nonparametric linkage analyses in a genome-wide scan, …

[HTML][HTML] Biomarkers of bipolar disorder: specific or shared with schizophrenia?

F Bellivier, PA Geoffroy, J Scott, F Schurhoff… - Frontiers in …, 2013 - ncbi.nlm.nih.gov
… depression in the relatives of schizophrenic patients (14). A … from disease-specific genome-wide
association study (GWAS) … For example, multiplex immunoassay analyses were carried …

Principal components of heritability from neurocognitive domains differ between families with schizophrenia and control subjects

H Wiener, L Klei, M Calkins, J Wood… - Schizophrenia …, 2013 - academic.oup.com
… PCH3 apparently represents a heritable component of … Multiplex families included the proband
and one or more … is a standard threshold for linkage on a quantitative trait. It translates to a …