Genomewide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis

J Delgado‐Calle, AF Fernández, J Sainz… - Arthritis & …, 2013 - Wiley Online Library
… In this study, we aimed to compare the genome-wide methylation profiles of bone from … ,
genome-wide methylation profiling of bone samples reveals differentially methylated regions in …

Genome-wide profiling of bone reveals differentially methylated regions in osteoporosis and osteoarthritis

J Sainz, JA Riancho - 2013 - digital.csic.es
… [Conclusion]: Genome-wide methylation profiling of bone samples revealed differentially
methylated regions in OP and OA. These regions were enriched in genes associated with cell …

Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis

A Del Real, FM Pérez-Campo, AF Fernández… - Epigenetics, 2017 - Taylor & Francis
… of hMSCs in the pathogenesis of osteoporosis is still unclear. … data about the methylation
signature of skeletal hMSCs. … from fracture patients shows differentially methylated regions in …

[HTML][HTML] Relationship between osteoporosis and osteoarthritis based on DNA methylation

Y Li, B Xie, Z Jiang, B Yuan - International journal of clinical and …, 2019 - ncbi.nlm.nih.gov
… [23] studied the genome-wide methylation profile of the bones in patients with hip … genome-wide
methylation analysis of bone samples revealed the regions with differential methylation

DNA methylation signatures of bone metabolism in osteoporosis and osteoarthritis aging-related diseases: an updated review

VV Visconti, I Cariati, S Fittipaldi, R Iundusi… - International Journal of …, 2021 - mdpi.com
… , previously identified by a genome-wide association study as a novel … bone biopsies from
postmenopausal OP women, revealing … However, these differentially methylated regions of the …

Genomewide DNA methylation study identifies significant epigenomic changes in osteoarthritic subchondral bone and similarity to overlying cartilage

MA Jeffries, M Donica, LW Baker… - Arthritis & …, 2016 - Wiley Online Library
… with hip osteoarthritis (OA) and to compare these with DNA … In subchondral bone, we
identified differential methylation of … In the present study, the degree of osteoporosis in the …

Genomewide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage

MA Jeffries, M Donica, LW Baker… - Arthritis & …, 2014 - Wiley Online Library
… hypothesized that several differentially methylated CpG sites … , a population enriched in
osteoporosis, a practice that may … loci for osteoarthritis (arcOGEN): a genome-wide association …

… -wide DNA methylation study of hip and knee cartilage reveals embryonic organ and skeletal system morphogenesis as major pathways involved in osteoarthritis

E Aref-Eshghi, Y Zhang, M Liu, PE Harper… - BMC musculoskeletal …, 2015 - Springer
… We found a number of CpG sites differentially methylated in … according to their genome wide
DNA methylation profiling. … of patients with possible osteoporosis who may not necessarily …

Role of epigenomics in bone and cartilage disease

JBJ van Meurs, CG Boer… - Journal of Bone and …, 2019 - academic.oup.com
… For osteoporosis, this would be bone, but for osteoarthritis, … of pathways, differentially
methylated regions in the family of … in cartilage revealed 46 differentially expressed miRNAs in OA, …

Identification of DNA methylation changes associated with disease progression in subchondral bone with site-matched cartilage in knee osteoarthritis

Y Zhang, N Fukui, M Yahata, Y Katsuragawa… - Scientific Reports, 2016 - nature.com
genome-wide DNA methylation profiles in subchondral bone and identify the differential
methylated genes (… GO analysis of the 41 shared DMGs revealed higher enrichment folds in the …