… Cartilage and bone homeostasis is an important factor in OA pathology and can also be
influenced by epigenetics. Genome-wide methylation profiling reveals samples taken from bone …

… Here, we will describe current and potential new epigenetic studies that are likely to reveal
… osteoporosis trabecular bone genome-wide CpG methylation. The differentially methylated …

… future treatment options for early osteoarthritis (OA) of the hip … gene variants observed in
genome-wide association study (… individual exomic profiles associated with OA revealed clear …

… Recently, genome-wide association studies (GWASs) have … roles in bone homeostasis and
osteoporosis pathways and … The Volcano plot shows the significant lncRNAs that we found …

… articular cartilage, synovium, and subchondral bone [1]. It is … (96 combinations in total)
revealed 352 upregulated and 159 … is the first study to investigate genome-wide changes in gene …

… and sclerosis of the underlying bone. The disease … genome-wide analysis of the transcriptome
and methylome of articular cartilage revealed that only 24% of the differentially methylated …

… Osteoporosis (OP) is a systemic skeletal disease … rare variants obtained from genome wide
sequencing to complex … The hub differentially expressed genes with differential methylation …

… profile in aging bone, pathway analysis revealed few … of aged mouse bone DEGs are enriched
for genome‐wide associations … genetic factors for osteoporosis database. The dashed line …

… OA and the following factors: bone mineral density, childhood … In pursuit of this, genome-wide
buffy coat DNA methylation … another study identified differentially methylated areas as well …

… conditions, eg osteoporosis [12], osteoarthritis [13], … at the genome-wide level by RNA
sequencing or microarray in osteonecrotic tissues, mesenchymal stem cells (MSCs) and bone …