… -related diseases, including osteoporosis and osteoarthritis. … collection of all human
genome-wide association studies, and … methylation data and identified 451 differentially …

… a genome-wide methylation study in bone samples obtained from patients with severe hip
osteoarthritis … Our results revealed several genes showing differential methylation between …

… with osteoarthritis, large-scale genome-wide association … This study compared subchondral
bone underlying low-… heart disease and cluster C with osteoporosis [43] . Replication of the …

… arthritis and osteoarthritis. Besides … against differential methylation being just a consequence
of co-morbidities. Second, the sample size of our study is relatively small for genome-wide …

… The role of methylation in osteoarthritis has been studied in … radiographic changes of OA or
osteoporosis (densitometric T-score … is determined by a differential methylation pattern of their …

… of bone traits has advanced thanks in part to genome-wide … (SNPs) associated with
osteoarthritis, and over 2000 … Sites which were differentially methylated in bone and blood (…

… /CD40L system was revealed in bone metabolism regulation [105]. … genome-wide analyses
have recently been used in bone research. Lei et al. [59] performed gene expression profiling …

… development of genome-wide methylation and genome-wide … DNA methylation profiles; 3)
Differentially Methylated Regions … patients with Osteoporosis (OP), with an inverse methylation …

… of CARM1 unexpectedly revealed a close … bone samples, these differentially expressed
transcriptomic signatures should primarily refer to osteoporosis, as inflammatory osteoarthritis …

… , synovial inflammation and bone remodelling. Disease aetiology is … Replicated genome-wide
significant and genome-wide … upon the differentially methylated region. Furthermore, DNA …