Genetic dissection of canine hip dysplasia phenotypes and osteoarthritis reveals three novel loci
L Mikkola, S Holopainen, T Pessa-Morikawa… - BMC genomics, 2019 - Springer
… were noggin (NOG), a bone and joint developmental gene on … We report three loci with
genome-wide significance and two … as it has been shown to be differentially methylated in OA [55] …
genome-wide significance and two … as it has been shown to be differentially methylated in OA [55] …
Epigenetics of bone diseases
L Michou - Joint Bone Spine, 2018 - Elsevier
… A genome-wide methylation study was conducted on mesenchymal stem cells … osteoarthritis
[20]. Cells from the group with osteoporosis exhibited accelerated age-related methylation …
[20]. Cells from the group with osteoporosis exhibited accelerated age-related methylation …
Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis
J Steinberg, GRS Ritchie, TI Roumeliotis… - bioRxiv, 2016 - biorxiv.org
… progression, combining genome-wide DNA methylation, RNA … We also identified 271
differentially methylated regions (… to be differentially transcribed in osteoarthritic bone, consistent …
differentially methylated regions (… to be differentially transcribed in osteoarthritic bone, consistent …
Intraspecific and interspecific investigations of skeletal DNA methylation and femur morphology in primates
G Housman, EE Quillen… - American journal of …, 2020 - Wiley Online Library
… skeletal pathologies and disorders, such as osteoporosis … genome-wide and gene-specific
DNA methylation in primate … were significantly differentially methylated across comparative …
DNA methylation in primate … were significantly differentially methylated across comparative …
Epigenetic mechanisms and non-coding RNAs in osteoarthritis
… Here, we will describe current and potential new epigenetic studies that are likely to reveal
… osteoporosis trabecular bone genome-wide CpG methylation. The differentially methylated …
… osteoporosis trabecular bone genome-wide CpG methylation. The differentially methylated …
[HTML][HTML] DNA methylation analysis identifies key transcription factors involved in mesenchymal stem cell osteogenic differentiation
… our osteoblastogenesis differentially methylated regions with … osteoarthritis where osteoporotic
and sclerotic bone regions … seq information about the genome-wide binding sites for 161 …
and sclerotic bone regions … seq information about the genome-wide binding sites for 161 …
Epigenetics of osteoporosis: critical analysis of epigenetic epidemiology studies
JA Riancho - Current Genomics, 2015 - ingentaconnect.com
… in DNA methylation between osteoporosis and osteoarthritis, … , among the genes differentially
methylated we found several … Epigenome-wide studies explore potential between-group dif…
methylated we found several … Epigenome-wide studies explore potential between-group dif…
Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus
S Hackinger, K Trajanoska… - Human molecular …, 2017 - academic.oup.com
… have been carried out by the Genetic Factors for Osteoporosis (GEFOS) consortium: a
large-… on a genome-wide level. Here, we present results from the first genome-wide analysis …
large-… on a genome-wide level. Here, we present results from the first genome-wide analysis …
Epigenetic mechanisms in bone biology and osteoporosis: can they drive therapeutic choices?
F Marini, L Cianferotti, ML Brandi - International journal of molecular …, 2016 - mdpi.com
… A genome-wide study evaluated the DNA methylation profile, at the genome level (…
superfamily genes, differentially methylated between osteoporosis and osteoarthritis, include genes …
superfamily genes, differentially methylated between osteoporosis and osteoarthritis, include genes …
Pharmacogenomics of osteoporotic fractures
JA Riancho, FM Pérez-Campo - Pharmacogenomics in Drug Discovery …, 2014 - Springer
… differentially methylated regions were found in a recent genome-wide study that compared
CpG methylation in bone … patients with osteoporotic fractures and with osteoarthritis [42]. Thus…
CpG methylation in bone … patients with osteoporotic fractures and with osteoarthritis [42]. Thus…