[HTML][HTML] Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes

P Marambio, B Toro, C Sanhueza, R Troncoso… - … et Biophysica Acta (BBA …, 2010 - Elsevier
deprivation. In conclusion, glucose deprivation induces oxidative stress which is associated
with aggresome formation and activation of autophagy in cultured cardiac myocytes. …

Ubiquitinated-protein aggregates form in pancreatic β-cells during diabetes-induced oxidative stress and are regulated by autophagy

NA Kaniuk, M Kiraly, H Bates, M Vranic, A Volchuk… - Diabetes, 2007 - Am Diabetes Assoc
… induced by aminotriazole (ATZ) was sufficient to stimulate Ub-protein aggregate formation. …
Recently, we and others have described the formation of aggresome-like induced structures …

Emerging connections between oxidative stress, defective proteolysis, and metabolic diseases

T Homma, J Fujii - Free radical research, 2020 - Taylor & Francis
… delivers aggresomes to the growing autophagosomes for … oxidative stress is directly involved
in autophagy dysfunction. … complex and inhibits the late stage of autophagy that occurs at …

Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway

JF Moruno-Manchón, E Perez-Jimenez… - Biochemical …, 2013 - portlandpress.com
glucose inhibits autophagy, since its deprivation from cells cultured in full medium induces
autophagy … that glucose deprivation induces autophagy, thus suggesting an inhibitory role for …

Regulation of autophagy by glucose in mammalian cells

F Moruno, E Pérez-Jiménez, E Knecht - Cells, 2012 - mdpi.com
… , autophagy can be also stimulated by an … oxidative stress caused both by glucose deprivation
and hyperglycemia [85,90]. There are conflicting data about the role of p38 in autophagy. …

Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy

P Tannous, H Zhu, A Nemchenko, JM Berry… - Circulation, 2008 - Am Heart Assoc
… events that stimulate autophagic activity in stressed myocardium. Because autophagy is a
… Further evidence of aggresome formation was found when we coimmunostained for CryAB …

Impairment of autophagic flux promotes glucose reperfusion-induced neuro2A cell death after glucose deprivation

BG Jang, BY Choi, JH Kim, MJ Kim, M Sohn, SW Suh - PloS one, 2013 - journals.plos.org
autophagy and lysosomal dysfunction in hypoglycemia-induced neuronal death. In neuronal
cells, glucose reperfusion after glucose deprivation … /GR potentially inhibits autophagic flux …

[HTML][HTML] Autophagy: an integral component of the mammalian stress response

SW Ryter, AMK Choi - Journal of biochemical and …, 2013 - ncbi.nlm.nih.gov
… HDAC6 can organize ubiquitinated proteins into aggresome-… Loss of PINK1 function can
promote oxidative stress and … was required for the stimulation of autophagy by these agents [85]. …

Role of mitochondrial dysfunction, oxidative stress and autophagy in progression of Alzheimer's disease

V Bhatia, S Sharma - Journal of the neurological sciences, 2021 - Elsevier
… of cell constituents including proteasomes, aggresomes, and dysfunctional mitochondria as
… (tau protein phosphatase) stimulates neuronal autophagy, thus it providing a relationship …

Autophagic pathways and metabolic stress

S Kaushik, R Singh, AM Cuervo - Diabetes, Obesity and …, 2010 - Wiley Online Library
… nutritional deprivation, oxidative stress or organelle stress, basal activity of this pathway can
… autophagosome formation should benefit from interventions aimed at stimulating autophagy. …