[HTML][HTML] Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes
P Marambio, B Toro, C Sanhueza, R Troncoso… - … et Biophysica Acta (BBA …, 2010 - Elsevier
… deprivation. In conclusion, glucose deprivation induces oxidative stress which is associated
with aggresome formation and activation of autophagy in cultured cardiac myocytes. …
with aggresome formation and activation of autophagy in cultured cardiac myocytes. …
Ubiquitinated-protein aggregates form in pancreatic β-cells during diabetes-induced oxidative stress and are regulated by autophagy
NA Kaniuk, M Kiraly, H Bates, M Vranic, A Volchuk… - Diabetes, 2007 - Am Diabetes Assoc
… induced by aminotriazole (ATZ) was sufficient to stimulate Ub-protein aggregate formation. …
Recently, we and others have described the formation of aggresome-like induced structures …
Recently, we and others have described the formation of aggresome-like induced structures …
Emerging connections between oxidative stress, defective proteolysis, and metabolic diseases
T Homma, J Fujii - Free radical research, 2020 - Taylor & Francis
… delivers aggresomes to the growing autophagosomes for … oxidative stress is directly involved
in autophagy dysfunction. … complex and inhibits the late stage of autophagy that occurs at …
in autophagy dysfunction. … complex and inhibits the late stage of autophagy that occurs at …
Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway
JF Moruno-Manchón, E Perez-Jimenez… - Biochemical …, 2013 - portlandpress.com
… glucose inhibits autophagy, since its deprivation from cells cultured in full medium induces
autophagy … that glucose deprivation induces autophagy, thus suggesting an inhibitory role for …
autophagy … that glucose deprivation induces autophagy, thus suggesting an inhibitory role for …
Regulation of autophagy by glucose in mammalian cells
… , autophagy can be also stimulated by an … oxidative stress caused both by glucose deprivation
and hyperglycemia [85,90]. There are conflicting data about the role of p38 in autophagy. …
and hyperglycemia [85,90]. There are conflicting data about the role of p38 in autophagy. …
Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
P Tannous, H Zhu, A Nemchenko, JM Berry… - Circulation, 2008 - Am Heart Assoc
… events that stimulate autophagic activity in stressed myocardium. Because autophagy is a
… Further evidence of aggresome formation was found when we coimmunostained for CryAB …
… Further evidence of aggresome formation was found when we coimmunostained for CryAB …
Impairment of autophagic flux promotes glucose reperfusion-induced neuro2A cell death after glucose deprivation
… autophagy and lysosomal dysfunction in hypoglycemia-induced neuronal death. In neuronal
cells, glucose reperfusion after glucose deprivation … /GR potentially inhibits autophagic flux …
cells, glucose reperfusion after glucose deprivation … /GR potentially inhibits autophagic flux …
[HTML][HTML] Autophagy: an integral component of the mammalian stress response
SW Ryter, AMK Choi - Journal of biochemical and …, 2013 - ncbi.nlm.nih.gov
… HDAC6 can organize ubiquitinated proteins into aggresome-… Loss of PINK1 function can
promote oxidative stress and … was required for the stimulation of autophagy by these agents [85]. …
promote oxidative stress and … was required for the stimulation of autophagy by these agents [85]. …
Role of mitochondrial dysfunction, oxidative stress and autophagy in progression of Alzheimer's disease
V Bhatia, S Sharma - Journal of the neurological sciences, 2021 - Elsevier
… of cell constituents including proteasomes, aggresomes, and dysfunctional mitochondria as
… (tau protein phosphatase) stimulates neuronal autophagy, thus it providing a relationship …
… (tau protein phosphatase) stimulates neuronal autophagy, thus it providing a relationship …
Autophagic pathways and metabolic stress
… nutritional deprivation, oxidative stress or organelle stress, basal activity of this pathway can
… autophagosome formation should benefit from interventions aimed at stimulating autophagy. …
… autophagosome formation should benefit from interventions aimed at stimulating autophagy. …