[HTML][HTML] Ethanol-induced oxidant stress modulates hepatic autophagy and proteasome activity

TM Donohue Jr, PG Thomes - Redox biology, 2014 - Elsevier
… CYP2E1, oxidant generation by CYP2E1 stimulates formation of MD body-like aggresomes
that … Such an occurrence likely stimulates an equally rapid autophagic (perhaps mitophagic) …

Cell death and autophagy: cytokines, drugs, and nutritional factors

W Bursch, A Karwan, M Mayer, J Dornetshuber… - Toxicology, 2008 - Elsevier
… the formation of aggresomes, a potential trigger for autophagy. … , by stimulating catabolic
processes such as autophagy; class … autophagic cell death during glucose deprivation in the rat …

Emerging roles for the ubiquitin-proteasome system and autophagy in pancreatic β-cells

T Hartley, J Brumell, A Volchuk - American Journal of …, 2009 - journals.physiology.org
… for both stimulating peripheral tissue glucose uptake and … proteins that accumulate in
aggresome-like structures (ALIS) … increase mitochondrial and oxidative stress can cause protein …

[HTML][HTML] p53-regulated autophagy is controlled by glycolysis and determines cell fate

L Duan, RE Perez, B Davaadelger, EN Dedkova… - Oncotarget, 2015 - ncbi.nlm.nih.gov
… , though the mechanism of autophagy stimulation by glucose … can disrupt mitochondria
and increase oxidative stress [31, … We found p62 was localized in insoluble aggresomes with …

Inhibition of mitophagy decreases survival of Caenorhabditis elegans by increasing protein aggregation

M Civelek, JF Mehrkens, NM Carstens… - Molecular and Cellular …, 2019 - Springer
… species (ROS) leading to oxidative damage of DNA, lipids, … then for the elimination of the
aggresome [9], whereas the … to an increased flux through the autophagosomes but also by a …

Role of the ubiquitin-proteasome system and autophagy in regulation of insulin sensitivity in serum-starved 3T3-L1 adipocytes

Y Zhang, M Ye, LJ Chen, M Li, Z Tang, C Wang - Endocrine Journal, 2015 - jstage.jst.go.jp
… Several factors like oxidative stress, inflammation, mitochondrial dysfunction, endo… stimulated
control. To further confirm the impact of autophagy on insulin action, we blocked autophagy

… balance after thioredoxin reductase deficiency interrupts autophagy-lysosomal degradation pathway and enhances cell death in nutritionally stressed SH-SY5Y cells

P Nagakannan, MA Iqbal, A Yeung, JA Thliveris… - Free Radical Biology …, 2016 - Elsevier
… that excessive oxidative stress inhibits protein degradation … protein aggresome clearance,
eventually leading to cell death.. … In vitro models of oxygen and glucose deprivation, growth …

[HTML][HTML] Nutrient deprivation induces α-synuclein aggregation through endoplasmic reticulum stress response and SREBP2 pathway

P Jiang, M Gan, WL Lin, SHC Yen - Frontiers in Aging Neuroscience, 2014 - frontiersin.org
… LBs formation remains unknown, autophagy and ER stress … benefit from autophagy activation
elicited by nutrient deprivation (… autophagy reflected by increasing the level of autophagy

[HTML][HTML] The autophagy-lysosomal pathways and their emerging roles in modulating proteostasis in tumors

Z Dong, H Cui - Cells, 2018 - mdpi.com
… and substoichiometrically inhibits aggregates formation, thereby … stress, nutrient starvation,
oxidative stress, toxic stress, DNA … Actually, removal of disease-linked aggresomes by using …

How autophagy can restore proteostasis defects in multiple diseases?

V Joshi, A Upadhyay, VK Prajapati… - Medicinal Research …, 2020 - Wiley Online Library
Oxidative stress in plants activates autophagy that helps in … in autophagy functions give
rise to oxidative stress in normal … mTOR and in turn inhibits autophagy induction. The tumor …