… This review is the introduction to a special issue concerning, glutathione (GSH), the most
abundant … GSH plays critical roles in protecting cells from oxidative damage and the toxicity of …

… Although GSH efflux may be a mechanism to circumvent the normally protective role of
GSH, it appears essential for apoptosis to occur in many cell types [4], [36]. However, profound …

… Recently, this molecule has drawn much attention because of its interaction with other …
review, we have discussed the recent progress in GSH biosynthesis, metabolism and its role …

… in good agreement with its rate of synthesis derived from the incorporation … GSH may act
either directly as a protective agent by … The peroxide so formed diffuses into the lens where it is …

… Only when the protective capacities of these mechanisms are overwhelmed would injtiry …
feedback mechanism on the pathway for glutathione biosynthesis, it may be that GSH is …

… of biochemical processes, its synthesis takes place exclusively … In addition, this group of
constants is used to measure the … of protective, defensive, synthetic, or signaling roles in …

… The introduction and removal of sulfhydryl protective agents on a cysteine … overview, showing
the biosynthetic and metabolic pathways and illustrating the general physiological roles of …

… individuals should result in corresponding variations in their susceptibility to drugs and
toxins. An interesting study with mononuclear leukocytes measured activity towards trans-stilbene …

… amino acid precursors for GSH synthesis. Disturbances of this … In this article we will review
the current knowledge on the … of cysteine by astrocytes for the synthesis of GSH in neurons. …

… The subsequent changes in cytosolic redox state trigger GSH synthesis, with a subsequent
increase in the total glutathione pool, which occurs before the disappearance of nuclear …