[HTML][HTML] Handling the hurdles on the way to anti-tuberculosis drug development

PF Dalberto, EV De Souza, BL Abbadi… - Frontiers in …, 2020 - frontiersin.org
… by scientists interested in anti-TB drug development, which goes from massively testing …
This review presents some difficulties found along the TB drug development process and …

[PDF][PDF] Handling the Hurdles on the Way to Anti-tuberculosis Drug Development

CV Bizarro, EV de Souza, BL Abbadi… - Frontiers in …, 2020 - repositorio.pucrs.br
… by scientists interested in anti-TB drug development, which goes from massively testing …
This review presents some difficulties found along the TB drug development process and …

Drug discovery for tuberculosis: Bottlenecks and path forward

TS Balganesh, V Balasubramanian, SA Kumar - Current Science, 2004 - JSTOR
… Robotic liquid handling of treatment. The major shortcoming that co … of anti-tuberculosis
drugs are discussed below. … com Hurdles in the antituberculosis drug discovery path pound in …

[HTML][HTML] Recent therapeutic approaches for the management of tuberculosis: Challenges and opportunities

K Patil, S Bagade, S Bonde, S Sharma… - Biomedicine & …, 2018 - Elsevier
… the principal anti-tuberculosis drug has been developed to … Drug resistant tuberculosis
poses a major hurdle to control … industries in new drug discovery of anti-TB drugs, as it has a …

Antituberculosis drug repurposing: a new hope for tackling multi-challenging TB in timely manner

S Majeed, S Mehraj, Z Ahmad - Drug Repurposing-Molecular …, 2022 - books.google.com
… of drug discovery limits its progress in drug development [36]. … Hurdles in TB drug repurposing:
Upon entering and infecting … Nature Reviews Drug of novel anti-tuberculosis agents from …

Tackling drug-resistant tuberculosis: current trends and approaches

R Tandon, M Nath - Mini Reviews in Medicinal Chemistry, 2017 - ingentaconnect.com
development of resistant strains but also helps in managing … As we see drug development
is the first thing that we need to … ; which is one of the major hurdles in eliminating TB [165]. …

Drug re‐engineering and repurposing: A significant and rapid approach to tuberculosis drug discovery

DS Reddy, A Sinha, A Kumar, VK Saini - Archiv der Pharmazie, 2022 - Wiley Online Library
… in dealing withhurdles revealing new drug targets; and (d) the animal module used to
screen for in vivo assay does not predict accurate treatment duration. [ 17 ] Despite these hurdles, …

Challenges in drug discovery against tuberculosis

M Dwivedi, P Giri - Molecular Epidemiology Study of …, 2021 - books.google.com
… of MTB become a major hurdle in drug discovery to fight against … complex process as
antituberculosis drugs are mostly given … is a gradually developing bacteria which must be handled

[PDF][PDF] Incentives and disincentives for new anti-tuberculosis drug development: situational analysis

D Chang Blanc, P Nunn, Stop TB Initiative - 2000 - apps.who.int
development hurdles. The team can also identify ways that efforts to increase drug development
… By managing a variety of these ‘push’ and ‘pull’ dynamics, WHO can better shape and …

Antimicrobial peptides as novel anti-tuberculosis therapeutics

JP Silva, R Appelberg, FM Gama - Biotechnology advances, 2016 - Elsevier
… Additionally, we address the challenges of translational development from benchside to
bedside, evaluate the current development pipeline and analyze the expected global impact …