Human DNA glycosylases involved in the repair of oxidatively damaged DNA

H Ide, M Kotera - Biological and Pharmaceutical Bulletin, 2004 - jstage.jst.go.jp
… homologues of DNA glycosylases that were first found in bacteria. This review summarizes
… field of human DNA glycosylases involved in the repair of oxidative base damage. For some …

Identification and characterization of a human DNA glycosylase for repair of modified bases in oxidatively damaged DNA

TK Hazra, T Izumi, I Boldogh, B Imhoff… - Proceedings of the …, 2002 - National Acad Sciences
… genomic databases, we identified two candidate DNA glycosylases with sequence … of these
DNA glycosylases, and discuss its potential role in repair of oxidatively damaged bases via …

Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage

M Takao, H Aburatani, K Kobayashi… - Nucleic acids …, 1998 - academic.oup.com
… occurs, the responsible DNA repair … of human DNA glycosylases: hOGG1, hMYH and
hNTH1. A gene encoding for hOGG1 which excises 7,8-dihydro-8-oxoguanine (8-oxoG) from DNA

Base-excision repair of oxidative DNA damage by DNA glycosylases

M Dizdaroglu - … Research/Fundamental and Molecular Mechanisms of …, 2005 - Elsevier
Oxidative damage to DNA caused by free radicals and other oxidants generate base and …
lyase action is associated with DNA glycosylases specific for oxidatively modified DNA bases, …

Oxidative DNA damage & repair: an introduction

J Cadet, KJA Davies - Free Radical Biology and Medicine, 2017 - Elsevier
… how the three bacterial DNA glycosylases that recognize free radical-damaged bases, Nth,
… and cancer, and assist in repairing oxidatively damaged DNA to maintain genomic stability. …

The interacting pathways for prevention and repair of oxidative DNA damage

G Slupphaug, B Kavli, HE Krokan - Mutation Research/Fundamental and …, 2003 - Elsevier
… pathways for repair of … new DNA glycosylases that initiate BER of oxidative damage have
been identified. These have specificities overlapping with previously known DNA glycosylases

DNA glycosylases: in DNA repair and beyond

AL Jacobs, P Schär - Chromosoma, 2012 - Springer
… will focus on the mammalian DNA glycosylases, for which we … discuss their role in the repair
of DNA base lesions. We will … DNA repair, eg, in innate and adaptive immunity and in DNA

Repair of oxidatively induced DNA damage by DNA glycosylases: mechanisms of action, substrate specificities and excision kinetics

M Dizdaroglu, E Coskun, P Jaruga - Mutation Research/Reviews in …, 2017 - Elsevier
… of the simultaneous investigation of many DNA base lesions as substrates. … DNA glycosylases
have been found when these two different substrates were used. Some DNA glycosylases

DNA glycosylases search for and remove oxidized DNA bases

SS Wallace - Environmental and molecular mutagenesis, 2013 - Wiley Online Library
… roles that the oxidative DNA glycosylases play in mammalian … mammalian DNA glycosylases
search for damage in DNA in … what roles mutant DNA glycosylases play in human disease. …

Mitochondrial DNA repair of oxidative damage in mammalian cells

VA Bohr, T Stevnsner, NC de Souza-Pinto - Gene, 2002 - Elsevier
DNA glycosylases cut the DNA at sites of specific oxidative … blot, the repair of oxidative
damage at different genes can be … We have directly compared the level of oxidative DNA lesions …