… of gastric cancer, one of the leading causes of cancer death worldwide. Epigenetics refers to
the number of modifications of the chromatin structure that affect gene expression … EZH2, an …

… gastric cancers with a depressed growth pattern (Type IIc), and in infiltrative advanced gastric
… carcinogenesis, p53 expression is rarely exhibited by early gastric lesions, but increases …

… (16) showed, by immunohistochemical analysis, a correlation … pRb2/p130, was observed
in most of the T antigen–positive cases, suggesting that association between T antigen and p53 …

… levels are correlated with higher levels of p53 expression in gastric cancer, … of EZH2 will
affect the cell cycle via the p53 and p21 pathways. In the present study, we silenced EZH2, …

… with p21 (Cdkn1a, Waf1, Cip1). Expression of this protein is highly regulated by p53 and …
In the present study, statistically significant higher expression of p21 was observed in BOVs, …

… We then used immunohistochemistry to confirm that the protein levels of Cdkn2a … /p16
INK4a and Cdkn2b/p15 INK4b (encoded by Cdkn2a and Cdkn2b; Fig. 6). The INK4B-ARF-INK4A …

… control involved in determining the expression pattern of germline-specific genes, in …
expression was inversely correlated with that of EZH2 in Barrett’s esophagus and in gastric cancers …

… In the present study, we examined EZH2 mRNA and protein expression in ESCC tissues …
p53 could inhibit the transcription of EZH2 by binding to the promoter of EZH2 in prostate cancer…

… in the expression pattern of miRNA in normal and cancer cells [27]… in lung cancer and its
direct target is E2F and p53 (Table 13). … study, miR-135a is a tumor suppressor in gastric cancer. …

… temporally restricted sequential expression patterns of the fly … In this study, EZH2 expression
was a better predictor of clinical … 2 is correlated with poor prognosis in human gastric cancer. …