… potential therapeutic implications for the treatment of obesity. … by administering the compound
to obese db/db mice. The … tolerance test to gauge adaptive thermogenesis, another major …

… thermogenic capacity of the BAT, we investigated the effect of … cold intolerance in GCGKO
mice was partially ameliorated by … physiological roles in regulation of adaptive thermogenesis. …

… and anti-obesity effects. This study examined metabolic responses to acute and chronic β
3 -AR activation in wild-type C57Bl/6 mice and congenic mice lacking functional uncoupling …

… In the present study, we treated precursor adipocytes and obese mice … thermogenesis in
BAT, iWAT and skeletal muscle. Consequently, body weight gain and fatty liver in obese mice …

… prevented diet-induced obesity in mice 108 . Ryanodine receptor … Treatment of wild-type
mice with dantrolene, a blocker of … 4,34), the effects of cold on thermogenesis had been studied …

… FABP) impairs adaptive thermogenesis in mice in response to … In this study, we found that
the obese A-FABP KO mice have a … salutary effects of A-FABP on prevention of obesity through …

… the treatment of metabolic diseases, including obesity 4,5 . Here we show that mice expressing
… To determine the effect of more widespread AMPK activation, we crossed mice harboring …

… for the treatment of obesity and related metabolic disorders. … role in adaptive thermogenesis,
we used mice with an … -induced thermogenesis [11, 12], we first tested the impact of …

… effect of environmental temperature must be understood to ensure applicability of mouse
experiments to human obesity… one-third of energy expenditure in mice is devoted to maintaining …

… skeletal muscle and protects against diet-induced obesity. … having important implications
for weight gain and obesity. … Sln -/- mice after the high-fat diet was an adaptive response to …