[PDF][PDF] Activation of anxiogenic circuits instigates resistance to diet-induced obesity via increased energy expenditure

X Xie, H Yang, JJ An, J Houtz, JW Tan, H Xu, GY Liao… - Cell metabolism, 2019 - cell.com
… mutant mice were lean and resistant to diet-induced obesity (DIO) because of an increase in
basal metabolic rate and adaptive thermogenesis … We did not examine the effect of chronic …

[PDF][PDF] A role for the melatonin-related receptor GPR50 in leptin signaling, adaptive thermogenesis, and torpor

DA Bechtold, A Sidibe, BRC Saer, J Li, LE Hand… - Current biology, 2012 - cell.com
… 2/2 mice show resistance to dietinduced obesity, yet lose less weight when fasted [9]. … (L)
To assess the effects of leptin on feeding, we administered leptin at the onset of the dark phase …

[HTML][HTML] Cranberry polyphenolic extract exhibits an antiobesity effect on high-fat diet–fed mice through increased thermogenesis

F Zhou, J Guo, X Han, Y Gao, Q Chen, W Huang… - The Journal of …, 2020 - Elsevier
… This study investigated whether CPE can improve HFD-induced obesity in mice, revealing
that CPE treatment effectively improved HFD-induced body weight gain, glucose metabolism, …

In the absence of UCP1-mediated diet-induced thermogenesis, obesity is augmented even in the obesity-resistant 129S mouse strain

IHN Luijten, HM Feldmann… - American Journal …, 2019 - journals.physiology.org
adaptive thermogenic mechanisms apart from heat production through UCP1 (1, 16, 26).
However, it is clear from our results that in UCP1-KO mice there is no effect of adaptation to the …

[HTML][HTML] Adaptive changes in adipocyte gene expression differ in AKR/J and SWR/J mice during diet-induced obesity

V Prpic, MA Sabol, GE Jezek, TW Gettys… - The Journal of …, 2002 - Elsevier
… These studies show that the diet-induced obesity of AKR/J mice … the adaptive thermogenic
response to increased energy density. … We examined the effect of mouse strain and diet in the …

Gypenosides reduced the risk of overweight and insulin resistance in C57BL/6J mice through modulating adipose thermogenesis and gut microbiota

J Liu, Y Li, P Yang, J Wan, Q Chang… - Journal of agricultural …, 2017 - ACS Publications
… In this study, the effect of gypenosides on the risk of obesity and insulin resistance and their
… high-fat diet-induced obese mouse model. Their effects on gut microbiota composition were …

Cold-induced conversion of cholesterol to bile acids in mice shapes the gut microbiome and promotes adaptive thermogenesis

A Worthmann, C John, MC Rühlemann, M Baguhl… - Nature medicine, 2017 - nature.com
… levels contribute to beneficial effects of beige and brown adipocytes on obesity-associated …
regulate thermogenic responses, which have been described to occur in the BAT of mice and …

[HTML][HTML] Thyroid hormone–sympathetic interaction and adaptive thermogenesis are thyroid hormone receptor isoform–specific

MO Ribeiro, SD Carvalho, JJ Schultz… - The Journal of …, 2001 - Am Soc Clin Investig
… Hypothyroid mice were treated for 10 days with varying … pharmacologically, especially in
treatment of obesity (1). The … , but would also likely have potent cardiac effects. Further work to …

Inhibiting peripheral serotonin synthesis reduces obesity and metabolic dysfunction by promoting brown adipose tissue thermogenesis

JD Crane, R Palanivel, EP Mottillo, AL Bujak, H Wang… - Nature medicine, 2015 - nature.com
mice fed a high-fat diet (HFD) are protected from obesity, … was mediating the metabolic
effects in HFD-fed Tph1 −/− mice, we … adaptive thermogenesis in adipose tissue and attenuate …

Orphan nuclear receptor estrogen-related receptor α is essential for adaptive thermogenesis

JA Villena, MB Hock, WY Chang… - Proceedings of the …, 2007 - National Acad Sciences
… resistant to diet-induced obesity, phenotypes that are not … consequences of the lack of
ERRα on BAT function. We show that mice lacking ERRα are defective in nonshivering adaptive