In vivo response to biodegradable controlled antibiotic release systems

F Korkusuz, P Korkusuz, F Ekşioĝlu… - … Research: An Official …, 2001 - Wiley Online Library
… recent study, poly(3-hydroxybutyrate-co-4-hydroxybutyrate) [P… The two polymers used in
this study were produced and … cellular layer consisting of fibroblasts and round phagocytic …

Medical application of microbial biopolyesters polyhydroxyalkanoates

Q Wu, Y Wang, GQ Chen - Artificial Cells, Blood Substitutes, and …, 2009 - Taylor & Francis
… with other polymers, inorganic materials and growth factors to adjust their biocompatibility, …
This review summarizes the many achievements of PHA application in medical fields. …

The expression of cross-linked elastin by rabbit blood vessel smooth muscle cells cultured in polyhydroxyalkanoate scaffolds

ST Cheng, ZF Chen, GQ Chen - Biomaterials, 2008 - Elsevier
… copolyesters poly(3-hydroxybutyrate-co-4-hydroxybutyrate)s (… In this study, increasing 4HB
in the copolymers led to … due to its good biocompatibility including ability to promote elastin …

[PDF][PDF] Characterization and cytotoxicity of polyhydroxyalkanoate microparticles as adjuvant matrix for the immobilization of Pasteurella multocida whole-cell vaccine

S Mohamed, AA Amirul, AWM Effendy… - Journal of …, 2017 - researchgate.net
… The PHA is known for its biocompatibility and … compared to poly(3-hydroxybutyrate-co-4-hydroxybutyrate)
[P… Biosynthesis of P(3HB) and P(3HB-co-4HB) copolymer were attained …

Polyhydroxyalkanoate (PHA)/inorganic phase composites for tissue engineering applications

SK Misra, SP Valappil, I Roy, AR Boccaccini - Biomacromolecules, 2006 - ACS Publications
… 52,53 and lack of toxicity toward mouse fibroblast cell lines, 52 chondrocytes, 54 … poly(4-hydroxybutyrate)
[poly(4HB)] and copolymers of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) …

[PDF][PDF] Applications of polyhydroxyalkanoates in the medical industry

CJ Brigham, AJ Sinskey - International Journal of Biotechnology for …, 2012 - core.ac.uk
… Indeed, NIH 3T3 fibroblast cells have been shown to adhere and … poly(3-hydroxybutyrate-co-4hydroxybutyrate) …
This study found that with higher 4HB content in the copolymer, a milder …

Biomacromolecule immobilization: Grafting of fish-scale collagen peptides onto aminolyzed P (3HB-co-4HB) scaffolds as a potential wound dressing

S Vigneswari, V Murugaiyah, G Kaur… - Biomedical …, 2016 - iopscience.iop.org
… on various types and forms of polymers through the process of … architecture of poly(3-hydroxybutyrate-co-4-hydroxybutyrate)
(… and cell viability assays using L929 fibroblast cells. The P(…

[PDF][PDF] Biosynthesis and lipase-catalysed hydrolysis of 4-hydroxybutyrate-containing polyhydroxyalkanoates from Delftia acidovorans

DHE Ch'ng, WH Lee, K Sudesh - Mal J Microbiol, 2012 - researchgate.net
… the erosion rate of the copolymer in aqueous solutions of lipases (… and biocompatible
materials for medical applications. … to produce poly(3hydroxybutyrate-co-4-hydroxybutyrate-co-3-…

[PDF][PDF] Polyhydroxyalkanoates: bio-based microbial plastics and their properties

CY Loo, K Sudesh - Malaysian Polymer Journal, 2007 - researchgate.net
cell weight) D). Freeze-fracture image of the copolymer granules containing about 35 wt% (of
dry cell … 3HB-co-4HB) copolymer possesses good biocompatibility and is comparable to the …

[PDF][PDF] The influence of electrospinning parameters and drug loading on polyhydroxyalkanoate (PHA) nanofibers for drug delivery

YF Lee, N Sridewi, S Ramanathan… - International Journal of …, 2015 - researchgate.net
… Low molecular weight poly(3hydroxybutyrate-co-4-hydroxybutyrate) [P(3HB-co-95 mol% …
polymers. This in turn has encouraged the use of various biodegradable and/or biocompatible