Induction of apoptosis in HuH-7 cancer cells by monoterpene and β-carboline indole alkaloids isolated from the leaves of Tabernaemontana elegans
TA Mansoor, RM Ramalho, S Mulhovo… - Bioorganic & medicinal …, 2009 - Elsevier
… and one new (4) monoterpene indole alkaloid from the same specimen of Tabernaemontana
… activities of these monoterpene indole alkaloids (1–4) along with β-carboline alkaloids (5–7…
… activities of these monoterpene indole alkaloids (1–4) along with β-carboline alkaloids (5–7…
Recent development in indole derivatives as anticancer agent: A mechanistic approach
N Devi, K Kaur, A Biharee… - Anti-Cancer Agents in …, 2021 - ingentaconnect.com
… Indoles are reported to show anti-cancer activity via different mechanisms such as
apoptosis induction [21], regulation of estrogen receptor [22], aromatase inhibition [23], …
apoptosis induction [21], regulation of estrogen receptor [22], aromatase inhibition [23], …
Synthesis, anticancer and antioxidant properties of new indole and pyranoindole derivatives
D Iacopetta, A Catalano, J Ceramella, A Barbarossa… - Bioorganic …, 2020 - Elsevier
… Among them, the indole nucleus, due to its biodiversity and … anticancer agents [3]. Furthermore,
FDA approved the use of some naturally occurring indole alkaloids for anti-tumor activity, …
FDA approved the use of some naturally occurring indole alkaloids for anti-tumor activity, …
Indole alkaloids from marine resources: Understandings from therapeutic point of view to treat cancers
F Islam, Z Dehbia, M Zehravi, R Das… - Chemico-Biological …, 2023 - Elsevier
… discussed the anticancer effects of marine indole alkaloids. … clinical trial regarding anticancer
effect of indole alkaloids. … -derived indole alkaloids possess the ability to exhibit anticancer …
effect of indole alkaloids. … -derived indole alkaloids possess the ability to exhibit anticancer …
Alkaloids as cyclooxygenase inhibitors in anticancer drug discovery
… Alkaloids have shown very potent anticancer activities both in … them as leads for anticancer
drug discovery. Herein, we … of alkaloids including isoquinoline alkaloids, indole alkaloids…
drug discovery. Herein, we … of alkaloids including isoquinoline alkaloids, indole alkaloids…
[HTML][HTML] Chemical diversity and bioactivities of monoterpene indole alkaloids (MIAs) from six Apocynaceae genera
… Additionally, some species have shown antiplasmodial and anticancer activities [14]. Several
Apocynaceae MIAs have been used as anticancer, analgesic, anti-inflammatory and anti-…
Apocynaceae MIAs have been used as anticancer, analgesic, anti-inflammatory and anti-…
Indole derived anticancer agents
… and synthesize novel indole derivatives that can … of indole with isatin sulfonamide conjugates.
By substituting morpholino isatin at the third position of the indole ring, anticancer activity …
By substituting morpholino isatin at the third position of the indole ring, anticancer activity …
[HTML][HTML] Target-based anticancer indole derivatives and insight into structure‒activity relationship: A mechanistic review update (2018–2021)
A Dhiman, R Sharma, RK Singh - Acta Pharmaceutica Sinica B, 2022 - Elsevier
… The effects on anticancer activity of changing the ring substitution on indole to reveal the …
indole alkaloids, many researches have also been made in the areas of indole alkaloids from …
indole alkaloids, many researches have also been made in the areas of indole alkaloids from …
[HTML][HTML] Marine-derived indole alkaloids and their biological and pharmacological activities
… , anticancer, antidiabetic, and antiparasitic activities. This review reports the indole alkaloids
… of 2016–2021 and their relevant biological/pharmacological activities. The marine-derived …
… of 2016–2021 and their relevant biological/pharmacological activities. The marine-derived …
Cytotoxicity of the indole alkaloid reserpine from Rauwolfia serpentina against drug-resistant tumor cells
SAA Abdelfatah, T Efferth - Phytomedicine, 2015 - Elsevier
… Although the antihypertensive reserpine has already been described in the 1950s to reveal
anticancer activity in vivo, its true potential has not been recognized at that time to our point …
anticancer activity in vivo, its true potential has not been recognized at that time to our point …