Antimicrobial, antineoplastic and cytotoxic activities of indole alkaloids from Tabernaemontana divaricata (L.) R. Br.

B Singh, RA Sharma, GK Vyas - Current Pharmaceutical …, 2011 - ingentaconnect.com
… interest because the indole alkaloids, which are commonly, used for anti-inflammatory,
antifertility and antioxidant activities. The active sub-fractions and seven indole alkaloids obtained …

Antileishmanial Activity of an Indole Alkaloid fromPeschiera australis

JC Delorenzi, M Attias, CR Gattass… - Antimicrobial Agents …, 2001 - Am Soc Microbiol
… In this study, we show the leishmanicidal effects of a chloroform fraction (CLF) and a purified
indole alkaloid obtained from crude stem extract of Peschiera australis againstLeishmania …

Bisindolemethane derivatives as highly potent anticancer agents: synthesis, medicinal activity evaluation, cell-based compound discovery, and computational target …

A Bahuguna, A Singh, P Kumar, D Dhasmana… - Computers in Biology …, 2020 - Elsevier
… of indole alkaloids, especially bioindolemethane derivatives and their anticancer potential. …
the cyano group at R 4 showed the best anticancer activity when there is no group at R 1 , R …

[PDF][PDF] Recent insights into β-Carboline alkaloids with anticancer potential

KL Manasa, SS Yadav, D Srikanth, N Nagesh… - IOSR J. Pharm. Biol …, 2020 - academia.edu
… and synthetic indole alkaloids that possess a common tricyclic pyrido[3,4-b]indole ring with
… that influence of size of the linker for antitumor activity. Also demonstrated the enhanced …

Alkaloids as anticancer agents: a review of chinese patents in recent 5 years

H Tao, L Zuo, H Xu, C Li, G Qiao… - … on Anti-Cancer Drug …, 2020 - ingentaconnect.com
… found alkaloids displayed potent anticancer activity both in vitro and in vivo, and some of the
anticancer alkaloids … 1c), an indole alkaloid isolated from sponge Fascaplysinopsis sp., can …

Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids)

P Dey, A Kundu, A Kumar, M Gupta, BM Lee… - Recent advances in …, 2020 - Elsevier
… significant anticancer activity against human (SK-MEL-37) melanoma cells with a possible
mechanism … The brominated tris-indole alkaloid gelliusine A (isolated from a deep-water new …

Structural optimization of indole derivatives acting at colchicine binding site as potential anticancer agents

DJ Hwang, J Wang, W Li, DD Miller - ACS medicinal chemistry …, 2015 - ACS Publications
A new series of indole analogues based on our earlier lead compound, 2-(1H-indol-5-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine
(42), was prepared as tubulin inhibitors in …

Alkylated monoterpene indole alkaloid derivatives as potent P-glycoprotein inhibitors in resistant cancer cells

DSP Cardoso, A Kincses, M Nové, G Spengler… - European Journal of …, 2021 - Elsevier
… -activity relationships (SAR) for optimizing monoterpene indole alkaloids as MDR-reversers,
in this study a new set of analogs was generated by alkylation of the indole nitrogen of both …

[HTML][HTML] Indole alkaloids from plants as potential leads for antidepressant drugs: A mini review

HA Hamid, ANM Ramli, MM Yusoff - Frontiers in pharmacology, 2017 - frontiersin.org
indole alkaloids isolated with antidepressant activity. This review provides information on the
potential of natural indole alkaloids for … disorder, structure-activity relationship studies, and …

[PDF][PDF] Synthetic indole alkaloids in cancer: an overview

R Singla, V Singh, A Negi - Adv. J. Pharm. Life sci. Res, 2013 - researchgate.net
… In recent years numerous natural occurring and synthetics indole alkaloids were isolated
or prepared and shown commendable\appreciable anticancer activity. Their potential can be …