The role of heterodimerization between VEGFR-1 and VEGFR-2 in the regulation of endothelial cell homeostasis

MJ Cudmore, PW Hewett, S Ahmad, KQ Wang… - Nature …, 2012 - nature.com
… (g) VEGFR-1, VEGFR-2 and neuropilin-1 were knocked down in … Recent computer modelling
of VEGF receptor subunit … of the VEGF-E:PlGF-1 heterodimer, we performed various in vitro

Effect of tumor microenvironment on tumor VEGF during anti-VEGF treatment: systems biology predictions

SD Finley, AS Popel - JNCI: Journal of the National Cancer …, 2013 - academic.oup.com
… receptors (VEGFR1 and VEGFR2), and coreceptor neuropilins (… In conclusion, our
molecular-detailed computational model is … and its soluble receptors, VEGFR-1 and VEGFR-2

[引用][C] AS Popel Interactions of VEGF isoforms with VEGFR-1, VEGFR-2, and neuropilin in vivo: A computational model of human skeletal muscle., 2007, 292, pp

F Mac Gabhann - H459-H474. DOI: https://doi. org/10.1152/ajpheart

[图书][B] VEGF in Development

C Ruhrberg - 2008 - Springer
… the human and murine VEGF isoforms. The gene encoding … carcinoma cells in vitro in a
neuropilin-dependent manner, … with VEGF occur in vivo, and that these interactions can directly …

[PDF][PDF] Supplemental File S1–Detailed description of computational model

QWAD Arnheim, SD Finley - rs.figshare.com
… receptors called neuropilins (NRP1 and NRP2) that bind VEGF directly … 1999 In vivo
assessment of vascular endothelial growth factor-induced … 2000 The interaction of neuropilin-1 …

Vascular endothelial growth factor-B in physiology and disease

M Bry, R Kivelä, VM Leppänen… - Physiological …, 2014 - journals.physiology.org
… ) and the neuropilin-1 (NRP-1) coreceptor, which are … crosstalk between VEGFR-1 and
VEGFR-2, in part via VEGF/PlGF … , and the in vitro and in vivo effects of VEGF-B were dependent …

[引用][C] Interactions of VEGF isoforms with VEGFR-1

F MacGabhann, AS Popel - … vivo: a computational model of human skeletal muscle

Antiangiogenic and antitumor activities of peptide inhibiting the vascular endothelial growth factor binding to neuropilin-1

A Starzec, R Vassy, A Martin, M Lecouvey… - Life sciences, 2006 - Elsevier
VEGFR-2 (KDR) or NRP-1. Antiangiogenic activity of the peptide was tested in vitro in
tubulogenesis assays and in vivo … -1 but not to tyrosine kinase receptors, VEGFR-1 (flt-1) and KDR; …

Neuropilin-1 Is Essential for Enhanced VEGF165-Mediated Vasodilatation in Collateral-Dependent Coronary Arterioles of Exercise-Trained Pigs

JA Fogarty, MD Delp, JM Muller-Delp… - Journal of vascular …, 2009 - karger.com
… regions and studied by in vitro videomicroscopy or frozen for … observation that both VEGFR-1
and VEGFR-2 protein levels … in the presence of neuropilin-1: a computational model. Am J …

Vascular endothelial growth factor receptor-2 in breast cancer

S Guo, LS Colbert, M Fuller, Y Zhang… - … et Biophysica Acta (BBA …, 2010 - Elsevier
… enhances VEGF-induced angiogenesis in vitro and in vivo and … to VEGFR-1 but also to
VEGFR-2/VEGFR-1 heterodimers. … to the VEGFR-2 promoter and that these interactions are not …