… to associate with Neuropilin-1. … In the current model, we assume that only free VEGF can
interact with … While the diffusivities of various VEGF isoforms would be different in vivo, we …

… in vitro cell culture systems and an in vivo zebrafish model, … VPF/VEGF-induced EC survival
independent of VEGFR-2. … , since VPF/VEGF receptors VEGFR-1 and VEGFR-2 are also …

… by neuropilin 2 that exhibited a parallel profile to VEGF-D. … in vivo; VEGF-A and -B for blood
vessel formation and VEGF-… of VEGFR-2 and -3 in rBMSC; however, mRNA for VEGFR-1 was …

… receptor 2 (VEGFR-2) but cannot bind to the neuropilin receptor… VEGFR-1 and VEGFR-2 are
expressed in endothelial cells … vitro experiments to determine whether Wnt5a leads to VEGF-…

… vitro and micro vessel growth ex vivo, and maintained the capacity to bind to the receptors
neuropilin-1, VEGFR-1, and VEGFR-2… density in cardiac and skeletal muscle also depend on …

… and that this effect is mediated by VEGFR-2. Tumor-derived … and VEGF188; the VEGFR-1
flt-1; the VEGFR-2 flk-1/KDR; … receptor-1/flt-1 and coreceptor neuropilin-1 but not Angs or their …

… of VEGFR-1 has higher affinity for VEGF than VEGFR-2, and … in in vivo models, most of what
we know about VEGFR-2 … how VEGFR-2 acts as a mechanoreceptor and closely interacts …

… Inherent limitations of in vitro/in vivo models and chronology … family: VEGFR-1 (fms-like
tyrosine kinase-1), VEGFR-2 (kinase … Neuropilins have a short cytoplasmic tail, with no known …

… domain of VEGFR-2, blocks VEGF–VEGFR-2 interaction and … of VEGFR-1 and the third
Ig domain of VEGFR-2 fused to the … VEGF co-receptors, such as HSPGs and neuropilins are …

… In vitro sNRP1 competes the binding of VEGF165 to EC … keratinocytes, and VEGFR-1 and
VEGFR-2 are expressed in the … Therefore, sNRP1 might interact directly with these other cell …