Vascular endothelial growth factor in the lung

NF Voelkel, RW Vandivier… - American Journal of …, 2006 - journals.physiology.org
… of VEGF have been demonstrated in in vitro and in vivo … PlGF regulates a number of genes
(136) including Flt-1, neuropilin-2, … out for VEGFR-1 but with intact VEGFR-2 (111). In addition, …

[HTML][HTML] Is neuropilin-1 the neuroimmune initiator of multi-system hyperinflammation in COVID-19?

K Saleki, P Alijanizadeh, A Azadmehr - Biomedicine & Pharmacotherapy, 2023 - Elsevier
… specific isoforms of vascular endothelial growth factor (VEGF), … These molecules directly
interact with VEGF receptors, … junction in vivo and in NSC-34 cells (a model of motor nerve cells). …

Multifaceted role of neuropilins in cancer

S Rizzolio, L Tamagnone - Current medicinal chemistry, 2011 - ingentaconnect.com
… to regulate neuropilins expression in tumor cells in vitro. Hypoxia, … By using a computational
model, it has been predicted that a … and its receptors (VEGFR-1, VEGFR-2, neuropilin-1) are …

VEGF-B: a survival, or an angiogenic factor?

X Li, C Lee, Z Tang, F Zhang, P Arjunan… - Cell adhesion & …, 2009 - Taylor & Francis
… (VEGFR-1, 2 and 3) and the semaphorin receptors neuropilin (… -D, into rabbit hindlimb skeletal
muscles induced strong … we found that in vitro, VEGFR-1 neutralizing antibody abolished …

Design principles for therapeutic angiogenic materials

PS Briquez, LE Clegg, MM Martino… - Nature Reviews …, 2016 - nature.com
… co-receptor neuropilin 1 (NRP1) 54 . By contrast, the shorter … bound to the ECM than is free
in skeletal muscle 80 . Another … , in vivo systems and computational models. These efforts will …

Ligand-specific differences in VEGFR-2 activation in response to VEGF-A and VEGF-E binding

O Li - 2021 - ourarchive.otago.ac.nz
… and interaction with other co-receptors such as neuropilins [… identify that VEGF-A binds to
both VEGFR-1 and VEGFR-2 in … like VEGF-A does, with evidence both in vivo and vitro [55, 58…

VEGF-A and the induction of pathological angiogenesis

JA Nagy, AM Dvorak, HF Dvorak - Annu. Rev. Pathol. Mech. Dis., 2007 - annualreviews.org
VEGFR-1 and VEGFR-2 are widely expressed by normal vascular endothelium in vivo and
also by cultured endothelial cells; VEGFR-2 … , neuropilin-1 and -2 (Nrp-1, Nrp-2), also interact

ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis, and tumor growth following oral administration

SR Wedge, DJ Ogilvie, M Dukes, J Kendrew, R Chester… - Cancer research, 2002 - AACR
… have been shown recently to bind to neuropilin 1 and 2 … the biological significance of these
interactions remains to be fully … of human xenograft and syngeneic tumor models in vivo. The …

[HTML][HTML] Discovery of high-affinity PDGF-VEGFR interactions: redefining RTK dynamics

SB Mamer, S Chen, JC Weddell, A Palasz… - Scientific reports, 2017 - nature.com
… and co-receptors: neuropilin-1 and neuropilin-2 leading to the … -family binding interactions
via computational modeling and … functional vascular anastomoses in vivo. Proceedings of the …

In silico modeling of angiogenesis at multiple scales: From nanoscale to organ system

AA Qutub, F Mac Gabhann… - … of particle interactions …, 2010 - books.google.com
… , we created a computational model that simulated in vitro cell … Interactions of VEGF isoforms
with VEGFR-1, VEGFR-2, and neuropilin in vivo: a computational model of human skeletal