… factor receptor (PDGFR) and epidermal growth factor … ubiquitination is thought to serve as
an internalization signal and … /UBPY also regulates the level of ubiquitination of other endocytic …

… Cbl and coordinate the ubiquitination and degradation of the epidermal growth factor receptor
[11]. … the plasticity and dynamics of ITSN1 function in endocytosis and signal transduction. …

… adaptor protein AP2, epsin or intersectin and CDE-mediated … factor 1 receptor (CSF1R),
Epidermal growth factor receptor (… EGFR leading to EGFR ubiquitination and degradation (47). …

… signaling through the ubiquitination and subsequent endocytosis and trafficking of epidermal
growth factor (… eukaryotes, a number of growth factor receptors activate the catalytic p110 …

… receptor endocytosis and degradation provide spatial and temporal regulation of signaling
… an important connection between receptor ubiquitination, endocytosis, and ligand-mediated …

… Thus, this ubiquitination would 235 need to be specific to … -bound protein 2, ITSN1 383
intersectin 1, NUMB protein numb … analysis of the epidermal growth factor receptor 434 (EGFR) …

… signaling switch that links trafficking events to the control of cell … Cdc42 controls secretory
and endocytic transport to the … increased levels of epidermal growth factor receptors (EGFRs) [ …

… the role of ubiquitination in RTK endocytosis is based on the … to AP-2 and intersectin, thus
mediating internalization of EGFR … Down-regulation of the epidermal growth factor receptor in …

… growth factor-α (TGF-α)-mediated epidermal growth factor … , thereby preventing basal
endocytosis and degradation of … of protein ubiquitination in regulating cytokine signaling and IFN-…

… of both E-cadherin and FGFR1 in response to FGF stimulation, we next examined a
possible direct role for E-cadherin in regulating the internalization and nuclear translocation of …