Regulatory mechanisms of melanogenesis: beyond the tyrosinase concept

G Prota - Journal of investigative dermatology, 1993 - Elsevier
… melanoma cells have revealed that the ratio cysdopas: dopa is … Kagedal B: The stability of
5-S-cysteinyldopa and 6-hydroxy-… formation in melanogenic subcompartment of pigment cells (…

Cysteine transport in melanosomes from murine melanocytes

SB Potterf, V Virador, K Wakamatsu… - Pigment cell …, 1999 - Wiley Online Library
… Capture of thiols by DOPAquinone effectively shifts pigmentation … detected tyrosine,
phenylalanine, DOPA, cysteine, and other … ( 1996) Modulation of 5-S-cysteinyldopa formation by …

[PDF][PDF] Development and characterization of a murine monoclonal antibody (MoAb), 6D4, against the precursor of pheomelanin, 5-S-cysteinyldopa (5-S-Cd)

J Liu - 1993 - era.library.ualberta.ca
… conversion of tyrosine to dopa and thence to dopaquinone … Racial differences in melanin
pigmentation are not due to the … melanin pigments and the pattern of distribution of the pigment

Urinary excretion of 5-S-cysteinyldopa in relation to skin type, UVB-induced erythema, and melanocyte proliferation in human skin

U Stierner, I Rosdahl, A Augustsson… - Journal of investigative …, 1988 - Elsevier
… in pigment cells with minimal pigment formation. Acta Derm … H, Rosengren E: 5-S-cysteinyldopa,
dopa and dopamine in the … Biological, molecular and clinical aspects of pigmentation. …

[PDF][PDF] Microdialysis as a Tool in Studies of L-Dopa and Metabolites in Malignant Melanoma and Parkinson's Disease

N Dizdar - 1999 - Citeseer
… of 5-S-cysteinyldopa (an intermediate pigment metabolite), … with irregular margins and
variable pigmentation. c) Nodular … of L-dopa treatment on 5-S-cysteinyldopa and on melanoma …

Dynamics of melanogenesis intermediates

S Pavel - Journal of investigative dermatology, 1993 - Elsevier
… transporter between extra- and intracellular amino acids … -bound forms of dopa together
with 5-S-cysteinyldopa (5-S-CD) … that COMT from the pigment-forming cells could be partly …

Chemistry 15 of Melanins

S Ito, K Wakamatsu - The Pigmentary System: Physiology and …, 2008 - books.google.com
… 5-S-cysteinyldopa in the urine of melanoma patients. 5-S-Cysteinyldopa is now widely used
as … renal clearance, make 5-S-cysteinyldopa a useful marker of pigmentation in normal and …

Metabolic basis and clinical evidence for skin lightening effects of thiol compounds

YC Boo - Antioxidants, 2022 - mdpi.com
… or decrease can cause serious pigmentation disorders. The melanin pigment of the skin
is … 6-S-Glutathionyl dopa is also formed at a lower yield (5%) compared to 5-S-glutathionyl …

Photochemistry and photobiology of melanogenic metabolites: formation of free radicals

WH Koch, MR Chedekel - Photochemistry and photobiology, 1987 - Wiley Online Library
… exist in humans with different pigmentation is unknown. … may be formed and found in actively
pigmenting melanocytes in … Free and protein-bound DOPA and 5-S-cysteinyldopa in B16 …

[HTML][HTML] Melanins: skin pigments and much more—types, structural models, biological functions, and formation routes

F Solano - New Journal of Science, 2014 - hindawi.com
… the dopaquinone ring, but the 5-S-cysteinyldopa (Figure 1(b)… On the other hand, the total
absence of pigmentation results in … Formation of polymers using L-dopa or DHI as precursor …