An estimate of the melanocyte mass in humans

I Rosdahl, H Rorsman - Journal of investigative dermatology, 1983 - Elsevier
… in serum concentrations of 5-S-cysteinyldopa following PUV A (… the system as though all
pigment-producing melanocytes in … Despite dopa incubation and the thin plastic sections, it was …

Bomirski melanomas-a versatile and powerful model for pigment cell and melanoma research

A SLOMINSKI, R PAUs - International journal of …, 1993 - spandidos-publications.com
… It was characterized by high tyrosinase activity, low pigmentation and a slower … Intracellular
distribution of dopa and 5-Scysteinyldopa in pigmented cells with minimal pigment formation

Regulation of yellow pigment formation in mice: a historical perspective

GL Wolff - Pigment Cell Research, 2003 - Wiley Online Library
… activity in pigment cells increases 5-S-cysteinyldopa(5-S-CD) … -CD:DOPA ratio and the
melanogenic activity of pigment cells. … no yellow pigment was detected, the sparse pigmentation of …

Neuromelanin in human dopamine neurons: comparison with peripheral melanins and relevance to Parkinson's disease

H Fedorow, F Tribl, G Halliday, M Gerlach… - Progress in …, 2005 - Elsevier
… be indicative of dopa-derived indole-type monomers in natural pigment, … pigmentation in
each neuron with age. This increase in intracellular NM with age may suggest that the pigment

Photodegradation of eumelanin and pheomelanin and its pathophysiological implications

S Ito, K Wakamatsu, T Sarna - Photochemistry and …, 2018 - Wiley Online Library
… oxidation of 5-S-cysteinyldopa or a 1:1 mixture of DOPA and … of the degree of pigmentation,
the pheomelanin being mostly … cell lines showed that eumelanin is the predominant pigment

The red and the black

JD Simon, DN Peles - Accounts of chemical research, 2010 - ACS Publications
dopa to melanin; he named the participating enzyme, dopa-… of 5-S-cysteinyldopa as a
precursor to pheomelanin. (11) … of pigment produced; such reactivity occurs in cells expressing …

Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants …

N Dizdar, A Kullman, B Kågedal - Cancer chemotherapy and …, 2000 - Springer
… Thus we obtained recoveries of 5-S-cysteinyldopa, gluta… factor in the pigment forming
compartments of the cell. What … of L-dopa in the subcutaneous extracellular fluid and the blood …

Photobleaching of pheomelanin increases its phototoxic potential: Physicochemical studies of synthetic pheomelanin subjected to aerobic photolysis

A Zadlo, G Szewczyk, M Sarna… - Pigment cell & …, 2019 - Wiley Online Library
… from enzymatic oxidation of 5-S-cysteinyldopa, subjected to … greater than that of a synthetic
dopa-melanin (Figure S3). The W-… is the dominant type of pigmentation in Caucasians, the …

Comparative analysis of melanins and melanosomes produced by various coat color mutants

G Prota, ML Lamoreux, J Muller… - Pigment Cell …, 1995 - Wiley Online Library
… importance of melanins to visible pigmentation in the skin, … the hydroxylation of tyrosine to
DOPA; 2) DOPA oxidase activity was … showed that oxidation of 5-S-cysteinyldopa in alkaline me…

Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function

JD Simon, D Peles, K Wakamatsu… - Pigment cell & melanoma …, 2009 - Wiley Online Library
… oxidation of dopa in the presence of excess cysteine generates a high yield of 5-S-cysteinyldopa
(… of the degree of pigmentation while they produce eumelanin at levels proportional to …