Intrathoracic retention of insoluble hyaluronic acid and its absorption process in rats

A Uemura, S Ogawa, R Tanaka - The International Journal …, 2020 - journals.sagepub.com
… This study tested the intrathoracic retention of insoluble hyaluronic acid when inserted into
the thoracic cavity. It was deduced that insoluble hyaluronic acid inserted into the rat thoracic …

Elucidation of the time-dependent degradation process in insoluble hyaluronic acid formulations with a controlled degradation rate

A Uemura, S Ogawa, Y Isono… - Journal of Tissue …, 2019 - journals.sagepub.com
… was inserted subcutaneously into rats as well. The relationship … characteristics of the
hyaluronate are retained. The water-… swelling ratio and between IR absorption peak at 1740 cm –1 …

Interstitial matrix and transendothelial fluxes in normal lung

D Negrini, A Passi - Respiratory physiology & neurobiology, 2007 - Elsevier
… chemically interacting with hyaluronic acid and proteoglycans, … dimensional scaffold of
insoluble macromolecules arranged … to the maintenance of normally hydrated lung parenchyma. …

Hyaluronic Acid Based Functionalization of Nanodelivery Systems: A Promising Strategy for CD44-Receptors-Mediated Targeted Therapy of Lung Cancer

Z Hussain, AH Akbari, SH Barbuor… - Journal of Drug Delivery …, 2024 - Elsevier
… , and the presence of local intrathoracic or distant metastasis. … of A549/DDP xenograft mice
indicated promising anticancer … (TPGS), which is a water-soluble derivative of vitamin E and a …

Toxicology evaluation of drugs administered via uncommon routes: intranasal, intraocular, intrathecal/intraspinal, and intra-articular

A Emami, J Tepper, B Short, TL Yaksh… - … journal of toxicology, 2018 - journals.sagepub.com
… Lipid soluble drugs can also be absorbed via the lymphatics … For small rodents (mice and
rats), pipette application of bolus … material (such as hyaluronic acid) before superimposing …

[PDF][PDF] Injectable Hyaluronic Acid Hydrogels For The Delivery Of Cell-Based Therapeutics To The Heart

M Chen - core.ac.uk
retention is correlated with improved cardiac function, reduced scar fraction, and increased
vascular density in a rat MI … in a rat MI model using an injectable hyaluronic acid hydrogel and …

Inhaled drug delivery: Past, present, and future

L Yue, X Zhang, C Zhao, R Chen, X Chen, L Rao - Nano Today, 2023 - Elsevier
… by the accumulation of insoluble nanoformulations in the lungs … intrathoracic airway deposition
and alveolar retention in rat [143… powder and gemcitabine in rats with lung cancer through …

Therapeutic effect of decellularized extracellular matrix-based hydrogel for radiation esophagitis by 3D printed esophageal stent

DH Ha, S Chae, JY Lee, JY Kim, J Yoon, T Sen… - Biomaterials, 2021 - Elsevier
… Furthermore, we established a radiation esophagitis rat model … Our results suggest that
the swelling or water retention … membrane complex, and soluble factors, including laminin, …

Hypothermic machine perfusion of rat livers preserves endothelial cell function

H Xu, JX Zhang, JW Jones Jr, JH Southard… - …, 2004 - journals.lww.com
… Methods: Soluble CD30 levels prior to and after transplantation … Methods: Rat livers were
preserved using static cold-storage … determined by hyaluronic acid (HA) uptake and multiple …

HEPATOCYTE GROWTH FACTOR IMPROVES SURVIVAL OF STEATOTIC LIVER TRANSPLANTATION IN RATS

X Zhao, M Hayashi, S Kaihara, T Kaido… - …, 2004 - journals.lww.com
… Methods: Soluble CD30 levels prior to and after transplantation … Methods: Rat livers were
preserved using static cold-storage … determined by hyaluronic acid (HA) uptake and multiple …