… The goals of this study were to determine the direct effect of the drug in the lung damage
occurring after intratracheal AD administration and to identify the location of the damage. Also, …

… in which male F344 rats were instilled intratracheally (it) with … cellular death or damage to
lung airway and parenchymal cells. … an intratracheal bolus instillation of AD directly to the lungs. …

… Each rat lung was cut into small pieces, fixed immediately in … bronchioles and around
pulmonary and bronchial arterioles (… that vitamin E reduces the pulmonary damage after AM admin…

… Syrian hamsters treated intratracheally with amiodarone (1.5 … The probe identified parenchymal
cells as the origins of TGF-… pulmonary fibrosis, a prolonged cytotoxic insult to the airway …

… Our rats received 175 mg/(kg day) of amiodarone, similarly to … alveolar, blood-vessel and
bronchial walls were similar in all … of the lung after 6 weeks of amiodarone (intratracheal single …

… amiodarone instillation produces rapid and massive damage to the alveolar–capillary barrier
and death to lung airway and parenchymal … that intratracheal administration of amiodarone …

… stem cell was administrated immediately after amiodarone suspension . Lung samples were
… stem cell therapy)revealed moderate improvement of lung injury.Conclusion: The majority of …

… 4), marked necrosis and desquamation of bronchial … of the lung of the AM-treated group
showed tissue injury in the … in Fischer 344 rats during amiodarone-induced pulmonary fibrosis…

… larger vessels, and conductive airways and their surrounding … total lung and parenchyma
volume 10 days after amiodarone … amiodarone-induced lung injury in rats in a quantitative way. …

… Finally, lung parenchyma also improved, suggesting that α-T … A second group of rats was
orally administered 5 mg α-T/100 … degree of lung injury caused by AD. The MDA levels in the …