Hepatoprotective effects of ginsenoside Rk3 in acetaminophen-induced liver injury in mice by activation of autophagy

L Qu, R Fu, X Ma, D Fan - Food & Function, 2021 - pubs.rsc.org
… the activation of Nrf2 and promoted the antioxidant pathway in … of Nrf2 expression ameliorates
APAP-induced hepatotoxicity. … induced the activation of Nrf2, suggesting a positive role of …

[HTML][HTML] Mechanism of drug-induced liver injury and hepatoprotective effects of natural drugs

Y Zhou, J Wang, D Zhang, J Liu, Q Wu, J Chen, P Tan… - Chinese medicine, 2021 - Springer
… dysfunction, ameliorate cholestasis, and … intervention effectively reduces the APAP-induced
liver damage. Its mechanism is not only related to activating the Nrf2 signaling pathway

[HTML][HTML] Dissecting the crosstalk between Nrf2 and NF-κB response pathways in drug-induced toxicity

W Gao, L Guo, Y Yang, Y Wang, S Xia… - Frontiers in cell and …, 2022 - frontiersin.org
APAP-induced hepatotoxicity by activating Nrf2 antioxidativehepatotoxicity, we focused
specifically on the role of Nrf2 and … , enhancement of the Nrf2 signaling pathway ameliorated AA-…

Thalictrum minus L. ameliorates particulate matter-induced acute lung injury in mice

R Badamjav, L Zhang, D Sonom, YH Wu, JP Kou… - Journal of …, 2021 - Elsevier
… inflammation via activating Nrf2 modulated by AMPK/Akt/GSK3β pathwayIsoorientin
ameliorates APAP-induced hepatotoxicity via activation Nrf2 antioxidative pathway: the involvement

… from Penthorum chinense Pursh suppresses HMGB1/TLR4/NF-κB signaling and NLRP3 inflammasome activation in acetaminophen-induced hepatotoxicity

YC Du, L Lai, H Zhang, FR Zhong, HL Cheng… - Food & function, 2020 - pubs.rsc.org
… exert a profound anti-inflammatory and antioxidant activity. In this study, … of KA against
APAP-induced hepatotoxicity in mice and … inflammation via activating the HMGB1/TLR4 pathway

[HTML][HTML] Penehyclidine hydrochloride inhibits renal ischemia/reperfusion-induced acute lung injury by activating the Nrf2 pathway

Z Liu, Y Li, L Yu, Y Chang, J Yu - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
… We also explored the effects of brusatol on the levels of antioxidant enzymes induced by Nrf2
(… Thus, the PHC-induced activation of the Nrf2 pathway may have ameliorated pulmonary …

[HTML][HTML] l-Carnitine counteracts in vitro fructose-induced hepatic steatosis through targeting oxidative stress markers

A Montesano, P Senesi, F Vacante, G Mollica… - Journal of …, 2020 - Springer
… including activation of farnesoid X receptor (FXR) that ameliorates … low glycemic index products
and antioxidant foods and, in … Nrf2 expression and that some natural products ameliorate

Kazinol B protects H9c2 cardiomyocytes from hypoxia/reoxygenation-induced cardiac injury by modulating the AKT/AMPK/Nrf2 signalling pathway

Q Zhang, YY Dang, X Luo, JJ Fu, ZC Zou… - Pharmaceutical …, 2023 - Taylor & Francis
… Thus, we suggested that AKT and AMPK pathways were involved in Nrf2 activation and
contributed to … but promoted antioxidant enzyme activity and the activation of the Nrf2/ARE/HO-1 …

Isoorientin alleviates UVB-induced skin injury by regulating mitochondrial ROS and cellular autophagy

H Zheng, M Zhang, H Luo, H Li - Biochemical and biophysical research …, 2019 - Elsevier
… natural products with antioxidant properties represents an … In conclusion, these results
indicated the photoprotective roleameliorate UVB-triggered photodamage in fibroblast through

Unveiling the therapeutic promise of natural products in alleviating drug‐induced liver injury: Present advancements and future prospects

D Singh, MA Khan, HR Siddique - Phytotherapy Research, 2024 - Wiley Online Library
hepatotoxicity via activating the Nrf2 signaling pathway, … treatment with apigenin has
ameliorated the histopathological … hepatoprotective effects against APAP-induced liver injury. Nagi …