… RNA and established Keth-seq as an effective method for transcriptome-wide RNA secondary
structure mapping in … in ssRNA, Keth-seq is able to map secondary structures such as rG4 …

… The key chemical advancement to enable keth-seq was the … The development of keth-seq
demonstrates the power of … RNA structure probing of HIV-1 RNA genome with DMS-MaP-…

… in a global RNA structuromics approach. In order to elucidate the transcriptome-wide RNA
… molecules, we conclude that Lead-seq is a suitable method to map RNA structures in vivo. …

… transcriptome-wide probing of RNA secondary structure using … applied to capture RNA
secondary structure in many studies, … contains diverse RNA structural mapping experiments, but …

… specifically labels single-stranded RNA in vivo and in vitro, and established Keth-seq as an
effective method for transcriptome-wide RNA secondary structure mapping in live cells. We …

… protocol for genome-wide ssDNA mapping and focus on its … , called Keth-seq, for RNA
secondary structure probing under … along with Keth-seq specific labeling of single-stranded RNA …

… adenines (A) and cytosines (C), Keth-seq reports N 3 -kethoxal-induced modification of …
) is merged with partial depth maps (similar to the available RNA structure scores). Finally, a …

… transcriptome-wide rG4 assays, containing rG4-seq, ligand-binding methods such as G4RP-seq
and chemical probing methods such as Keth-seq, … the transcriptome-wide experimental …

… complete structure profiles for transcriptome-wide RNAs are warranted and would greatly
promote the utility of RNA structure … Keth-seq for transcriptome-wide RNA structure mapping. …

… Here, we extend these studies with the first transcriptome-wide mapping method for cataloging
RNA solvent accessibility, icLASER. By combining solvent accessibility (icLASER) with …