Relationships Between RNA Polymerase II Activity and Spt Elongation Factors to Spt- Phenotype and Growth in Saccharomyces cerevisiae

P Cui, H Jin, MR Vutukuru… - G3: Genes, Genomes …, 2016 - academic.oup.com
… the relationship between RNA Polymerase II (Pol II) activity, functions of Spt elongation
factors, and cryptic transcription because of the previous observation that increased-activity Pol II

Yeast U6 snRNA made by RNA polymerase II is less stable but functional

KA Lipinski, J Chi, X Chen, AA Hoskins, DA Brow - RNA, 2022 - rnajournal.cshlp.org
… either the two U6 genes compete for transcription factors, … presumably transcribed by different
RNAPs, or that the RNAs compete … Thus, the rapid kinetics of glucose repression and U6-II

[PDF][PDF] Crystal structure of a transcribing RNA polymerase II complex reveals a complete transcription bubble

CO Barnes, M Calero, I Malik, BW Graham, H Spahr… - Molecular cell, 2015 - cell.com
… published structures of RNA Polymerase II (Pol II), structural details of Pol II engaging a …
-stabilized transcribing Pol II complexes, revealing the upstream duplex and full transcription

High‐resolution transcription maps reveal the widespread impact of roadblock termination in yeast

T Candelli, D Challal, JB Briand, J Boulay… - The EMBO …, 2018 - embopress.org
… for elongating RNA polymerase II, a range of DNA‐binding … sites of Sen1dependent
termination in vitro (Porrua & Libri, 2013). This is thought to be due to a kinetic competition between

Senataxin protects the genome: Implications for neurodegeneration and other abnormalities

MF Lavin, AJ Yeo, OJ Becherel - Rare Diseases, 2013 - Taylor & Francis
… Citation 20 showed that kinetic competition between elongating RNA pol II and … early Pol II
termination. Loss of Sen1p results in transient R-loop accumulation, giving rise to transcription-…

[HTML][HTML] Base J: blocking RNA polymerase's way

DZ Hazelbaker, S Buratowski - Current biology: CB, 2012 - ncbi.nlm.nih.gov
… to promote proper gene expression and prevent transcriptionalDNA base in Leishmania
blocks RNA Polymerase II and suggests an interesting new model for transcription termination. …

Rho directs widespread termination of intragenic and stable RNA transcription

JM Peters, RA Mooney, PF Kuan… - Proceedings of the …, 2009 - National Acad Sciences
… The transcription termination factor Rho is a global regulator of RNA polymerase (RNAP). …
Given the similarities of Rho-dependent and Sen1-dependent termination, one possibility is …

Senataxin suppresses the antiviral transcriptional response and controls viral biogenesis

MS Miller, A Rialdi, JSY Ho, M Tilove… - Nature …, 2015 - nature.com
… attenuates the activity of RNA polymerase II (RNAPII) at … , we first profiled viral growth
kinetics in human cells depleted of … can dynamically compete with IRF3-mediated transcription. …

Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing

W Mo, B Liu, H Zhang, X Jin, D Lu, Y Yu, Y Liu, J Jia… - Genome biology, 2021 - Springer
… , during which nascent RNA is released from the complex of RNA Polymerase II (Pol … The
kinetic competition between Pol II and exonuclease promotes termination [1, 2, 16]. As a result, …

Distinct transcription kinetics of pluripotent cell states

R Shao, B Kumar, K Lidschreiber… - Molecular Systems …, 2022 - embopress.org
RNA Pol II traverse encounters termination roadblocks imposed by DNA sequence or antisense
transcription … encounter stochastically determines if the polymerase comes to a complete …