[HTML][HTML] New algorithms improving PML risk stratification in MS patients treated with natalizumab

…, M Comabella, MA Hernández, M Espiño… - Frontiers in …, 2020 - frontiersin.org
… The absence of lipid-specific IgM oligoclonal bands was the best … We studied in a multicenter
cohort of multiple sclerosis … efficacy of this drug in the long term was demonstrated (24). …

[HTML][HTML] Oligoclonal M bands and cervical spinal cord lesions predict early secondary progressive multiple sclerosis

…, MT Sanz, M Carcelén-Gadea… - Frontiers in …, 2022 - frontiersin.org
… The CSF study included the determination of oligoclonal IgG … ), and lipid-specific oligoclonal
M bands (LS-OCMB) in CSF. … with poor prognosis in both the short term and long term (7). …

[PDF][PDF] ANTIBODY JCV-INDEX IN PATIENTS WITH MULTIPLE SCLEROSIS TREATED WITH DISEASE-MODIFYING THERAPY

MUDJ Kolcava - is.muni.cz
… evaluated the long term stability of anti-JCV antibody levels … Baseline antibody index of more
than 0.90 predicts stable … antibody index of less than 0.20, which remained negative in more …

[图书][B] Translational Neuroimmunology, Volume 8: Multiple Sclerosis

N Rezaei, N Yazdanpanah - 2023 - books.google.com
… for MS treatment as they have led to long-term sustainable remission in the treatment-free …
an urgent need to recognize and predict outcomes in an individual MS patient, which could …

[HTML][HTML] Treatment-related progressive multifocal leukoencephalopathy in multiple sclerosis: a comprehensive review of current evidence and future needs

E D'Amico, A Zanghì, C Leone, H Tumani, F Patti - Drug safety, 2016 - Springer
… We need new and stronger prediction tools for stratifying … of lipid-specific immunoglobulin M
oligoclonal bands in … long-life disease and the long-term outcomes for patients with MS need …

Magnetic Resonance Imaging Follow-up and JCV Serology in Multiple Sclerosis

M Kolasa - 2020 - trepo.tuni.fi
… process and monitoring of the disease course in multiple sclerosis (MS). However, routinely
… Whether volumetric and DTI-derived metrics could play prognostic roles in the prediction of …

From the prodromal stage of multiple sclerosis to disease prevention

RA Marrie, M Allegretta, LF Barcellos, B Bebo… - Nature Reviews …, 2022 - nature.com
… these associations, particularly long-term prospective studies of … and CSF, along with the
detection of lipid-specific antibodies, … Information about the accuracy of predictions, effective …

Re-evaluating the incidence of natalizumab-associated progressive multifocal leukoencephalopathy

J Borchardt, JR Berger - Multiple sclerosis and related disorders, 2016 - Elsevier
… as L-selectin and CSF lipid-specific IgM bands has the potential to … Importantly, these
predictions were highly consistent with the … The incidence of PML in natalizumab long-term safety …

[HTML][HTML] The role of B cells in primary progressive multiple sclerosis

JP Holloman, RC Axtell, NL Monson, GF Wu - Frontiers in Neurology, 2021 - frontiersin.org
… the presence of depleted CSF B and T cells … long-term CD20-targeted B cell depletion
therapy may impact plasma cells in treated patients and thereby alter antibody levels, but antibody

[HTML][HTML] Implications of lymphocyte anergy to glycolipids in multiple sclerosis (MS): iNKT cells may mediate the MS infectious trigger

EL Hogan, M Podbielska, J O'Keeffe - Journal of clinical & cellular …, 2013 - ncbi.nlm.nih.gov
… for these anti-GalCer antibodies in order to predict conversion to clinically definite MS.
Antibodies in … Pursuing the GL and lipid-specific cells in MS will yield insights into lipid use in anti-…