… To isolate mast cells, rats were anesthetized by CO 2 … 3 Rs mainly mediate Ca 2+ release
in pancreatic acinar cells, but … is associated with compound 48/80-induced histamine release …

… mast cells does not mediate … 48/80-induced MC degranulation, mCHI was induced 4 days
after the last 48/80 dosing. We reported previously that the same MC depletion protocol in rats …

… In conclusion, our results identify intercellular signaling mechanisms between mast cells,
enteric glia, and neurons that are mediated by histamine and altered by early-life stress. Higher …

… injection, each mouse was placed into the transparent cage over … No effects on His- and
compound 48/80-induced hyperalgesia … may be mediated through a His release from mast cells. …

… previously.4, 12 One microgram of compound 48/80 induced a partial degranulation of
choroidal … Mast cell degranulation mediates compound 48/80-induced hyperalgesia in mice …

… mediate calcium entry into mast cells are thus important therapeutic targets. The cation
conductances of mast cells … isolating BMMC or peritoneal mast cells from mice that are genetically …

… the capacity of R18 and R18D to induce mast cell degranulation, as well as RBC hemolysis,
which … , as well as the potential of the peptides to cause anaphylactoid mediated reactions in …

… corresponding receptors on itch-mediating sensory nerves. These … in mice and rats support
the essential role for mast cell-… a close association between mast cells and sensory nerves …

… hyperalgesia mice, … degranulation and de novo production of lipid mediators and cytokines
by the activation of transcriptional events, eg mediated by nuclear factor of activated T-cells (…

… mast cell degranulation and mediates its effects in the skin via H1 receptor [3, 5], is the
best-known experimental pruritogen [2, 3, 5, 7]. Other pruritogens such as compound … Tlr7–/–mice …