(-)-Asarinin inhibits mast cells activation as a Src family kinase inhibitor

Y Hou, T Hu, D Wei, J Gao, D Che, X Wang… - … of Biochemistry & Cell …, 2020 - Elsevier
… local and system anaphylaxis of mice in vivo. Further … mast cell line LAD2 cells were used
as a model to detect the effect of Asa on IgE-mediate calcium mobilization and degranulation. …

[HTML][HTML] Contact H ypersensitivity to Oxazolone Provokes Vulvar Mechanical Hyperalgesia in Mice

T Martinov, R Glenn-Finer, S Burley, E Tonc, E Balsells… - PloS one, 2013 - journals.plos.org
… shown that mast cell degranulation regulates compound 48/… hyperalgesia in mice,
which was abrogated by mast cell … ) Mast cell degranulation mediates compound 48/80-induced

Targeting mast cells: a new way to treat endometriosis

MM Binda, J Donnez, MM Dolmans - Expert opinion on therapeutic …, 2017 - Taylor & Francis
… [Citation44] recently investigated the role of MCs in the pathogenesis of estrogen-mediated
experimental endometriosis in rats. They developed an endometriosis model by …

… cigarette smoke extracts upon the release of β-hexosaminidase from RBL-2H3 basophilic leukaemia cells in response to substance P, compound 48/80, concanavalin …

CJ Fowler, M Sandberg, G Tiger - Inflammation Research, 2003 - Springer
… response to compound 48/80 induced by quercetin treatment … ‘a greater propensity for mast
cell-mediated injury in the smok… Mouse 3T3 fibroblasts induce rat basophilic leukemia (RBL-…

[HTML][HTML] Antipruritic effect of curcumin on histamine-induced itching in mice

HK Lee, SB Park, S Chang, SJ Jung - The Korean Journal of …, 2018 - ncbi.nlm.nih.gov
… at treating histamine- and compound 48/80-induced pruritus, which are mediated by TRPV1,
compound 48/80-induced mast cell degranulation and histamine release from mast cells [30…

Polysaccharide fraction isolated from Passiflora edulis inhibits the inflammatory response and the oxidative stress in mice

RO Silva, SRB Damasceno, TV Brito… - Journal of Pharmacy …, 2015 - academic.oup.com
… -oedematogenic effect is mediated by the … compound 48/80-induced paw oedema, suggesting
that its anti-oedematogenic effect is due, partly, to the prevention of mast cell degranulation

[HTML][HTML] Ixodes scapularis nymph saliva protein blocks host inflammation and complement-mediated killing of Lyme disease agent, Borrelia burgdorferi

E Bencosme-Cuevas, TK Kim, TT Nguyen… - Frontiers in Cellular …, 2023 - ncbi.nlm.nih.gov
… /c mice paw edema but did not significantly alter the mast cell … (A) Twelve retired female
BALB/c mice, divided into four … with saline, compound 48/80 (1 µg of mast cell degranulator), …

A novel synthetic small molecule DMFO targets Nrf2 in modulating proinflammatory/antioxidant mediators to ameliorate inflammation

G Mathew, A Sharma, RJ Pickering… - Free Radical …, 2018 - Taylor & Francis
… DMFO stabilised mast cells (MCs) in in-vitro A23187 and compound 48/80-induced assays.
… This confirms that the mast cell the stabilising activity of DMFO is mediated entirely by …

[HTML][HTML] Immune actions on the peripheral nervous system in pain

JA Liu, J Yu, CW Cheung - International journal of molecular sciences, 2021 - mdpi.com
compound 48/80 induced degranulation of mast cells and caused … -mediated vasodilation
and mast cell degranulation were found to be key mechanisms in driving migraine in a mouse

[HTML][HTML] Anti-allergic properties of curine, a bisbenzylisoquinoline alkaloid

J Ribeiro-Filho, MR Piuvezam, PT Bozza - Molecules, 2015 - mdpi.com
… (in vivo), which is mediated by calcium release from … the mouse model of allergic asthma,
we investigated the effectiveness of curine in inhibiting mast cell-dependent responses in mice […