[HTML][HTML] Hydrogen sulfide attenuates cigarette smoke-induced airway remodeling by upregulating SIRT1 signaling pathway

R Guan, J Wang, Z Cai, Z Li, L Wang, Y Li, J Xu, D Li… - Redox Biology, 2020 - Elsevier
… Airway remodeling is one of the characteristics for chronic obstructive pulmonary disease (…
epithelial cells via release and autocrine action of transforming growth factor (TGF)-β1 as well …

Biogenesis of hydrogen sulfide and thioethers by cystathionine beta-synthase

T Majtan, J Krijt, J Sokolová, M Křížková… - Antioxidants & redox …, 2018 - liebertpub.com
… Aims: The transsulfuration pathway enzymes cystathionine beta-synthase (CBS) and
cystathionine gamma-lyase are thought to be the major source of hydrogen sulfide (H 2 S). In this …

[HTML][HTML] Cystathionine β-Synthase Is Necessary for Axis Development in Vivo

S Prabhudesai, C Koceja, A Dey… - Frontiers in Cell and …, 2018 - frontiersin.org
… in facilitating embryonic growth and development. In summary, we have identified a novel
phenotype for cbsb in zebrafish using multiple approaches, and have demonstrated that cbsb …

Inhibition of hydrogen sulfide synthesis attenuates chemokine production and protects mice against acute pancreatitis and associated lung injury

R Tamizhselvi, PK Moore, M Bhatia - Pancreas, 2008 - journals.lww.com
growth factor, and antibiotics) and treated with or without cerulein (10 −7 M) at 37C in a shaker
water bath for 60 minutes. Mouse … , have been shown to induce H 2 S synthesis and CSE …

Hydrogen sulfide attenuates particulate matter-induced emphysema and airway inflammation through Nrf2-dependent manner

G Jia, S Yu, W Sun, J Yang, Y Wang, Y Qi… - Frontiers in …, 2020 - frontiersin.org
… Chronic obstructive pulmonary disease (COPD) is a disease characterized … spaces
enlargement and alveolar walls destrection (Bracke et al., 2006). The enlargement of alveolar …

Hydrogen sulfide alleviates cigarette smoke-induced COPD through inhibition of the TGF-β 1/smad pathway

L Wang, J Meng, C Wang, C Yang… - Experimental …, 2020 - journals.sagepub.com
pulmonary disease have not been reported. In this study, rats were treated with cigarette
smoke to create a chronic obstructive pulmonary disease … the transforming growth factor super …

Cystathionine βSynthase Regulates the Proliferation, Migration, and Invasion of Thyroid Carcinoma Cells

QY Jiang, JM Li, MR Jing, YX Zhang… - Oxidative Medicine …, 2022 - Wiley Online Library
… TPC-1 and ARO cells are widely adopted to establish subcutaneous xenograft tumor
models in nude mice [20, 36]. We then determined the effects of CBS on the growth of human …

Augmented H2S production via cystathionine-beta-synthase upregulation plays a role in pregnancy-associated uterine vasodilation

L Sheibani, TJ Lechuga, H Zhang… - Biology of …, 2017 - academic.oup.com
… to support fetal and placental growth, making UBF a critical rate-limiting factor for pregnancy
health. Constrained UBF results in intrauterine growth restriction, preeclampsia, and other …

Cystathionine is a novel substrate of cystine/glutamate transporter: implications for immune function

S Kobayashi, M Sato, T Kasakoshi, T Tsutsui… - Journal of Biological …, 2015 - ASBMB
… wild-type and xCT-deficient mice using capillary electrophoresis time-of-… mice cystathionine
was absent in the thymus and spleen of the xCT-deficient mice as compared with control mice

Hydrogen sulfide metabolism and pulmonary hypertension

L Roubenne, R Marthan, B Le Grand, C Guibert - Cells, 2021 - mdpi.com
air is altered in various hypoxic diseases, such as chronic obstructive pulmonary disease
(… with an improvement of alveolar growth and pulmonary vessel density in lungs. Vascular …