… microglial and macrophage activation traits determine the differential neuroinflammatory responses and analgesic effect of minocycline in chronic neuropathic pain
Z Li, H Wei, S Piirainen, Z Chen, E Kalso… - Brain, behavior, and …, 2016 - Elsevier
… mechanical allodynia regularly in this period (Fig. 5A). Interestingly, minocycline attenuated
mechanical allodynia … afterward, with the anti-allodynic effect being most prominent before …
mechanical allodynia … afterward, with the anti-allodynic effect being most prominent before …
Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy
M Zychowska, E Rojewska, G Kreiner, I Nalepa… - Journal of …, 2013 - Elsevier
… Mechanical allodynia was measured on the left and right paw … In the present study
minocycline attenuated allodynia and … upregulation of several proinflammatory cytokines and key …
minocycline attenuated allodynia and … upregulation of several proinflammatory cytokines and key …
[HTML][HTML] Minocycline attenuates bone cancer pain in rats by inhibiting NF-κB in spinal astrocytes
Z Song, B Xiong, X Guan, F Cao, A Manyande… - Acta Pharmacologica …, 2016 - nature.com
… in the expression of pro-inflammatory cytokines and chemokines. … of NF-κB in BCP rat
models induced by inoculating Walker 256 … , and its potential role is facilitating pain perception. …
models induced by inoculating Walker 256 … , and its potential role is facilitating pain perception. …
[HTML][HTML] … and p38 MAPK Inhibitors Suppress Development of Mechanical Allodynia in Both Sexes in a Mouse Model of Antiretroviral-Induced Neuropathic Pain
MW Alhadlaq, W Masocha - International Journal of Molecular Sciences, 2023 - mdpi.com
… increased release of pro-inflammatory cytokines, such … minocycline reduced mechanical
allodynia in animal models through microglia inhibition. Mechanical allodynia was attenuated …
allodynia in animal models through microglia inhibition. Mechanical allodynia was attenuated …
Chronic intrathecal infusion of minocycline prevents the development of spinal-nerve ligation-induced pain in rats
CS Lin, ML Tsaur, CC Chen, TY Wang… - … Anesthesia & Pain …, 2007 - rapm.bmj.com
… Inhibition of microglial activation attenuates the development but not existing … tenuates
mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. …
mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation. …
Effects of Etanercept and Minocycline in a rat model of spinal cord injury
F Marchand, C Tsantoulas, D Singh, J Grist… - … Journal of Pain, 2009 - Elsevier
… the effects on mechanical allodynia and microglial activation of … Several pro-inflammatory
cytokines and chemokines have … In addition, minocycline attenuated both microglial activation …
cytokines and chemokines have … In addition, minocycline attenuated both microglial activation …
Systemic administration of minocycline inhibits formalin-induced inflammatory pain in rat
… behavioral hypersensitivity in several rat models of pain facilitation, although this agent is …
In summary, minocycline attenuates inflammatory pain in a rat formalin model. Our results …
In summary, minocycline attenuates inflammatory pain in a rat formalin model. Our results …
Blockade of microglial activation reduces mechanical allodynia in rats with compression of the trigeminal ganglion
SR Han, GY Yang, MH Ahn, MJ Kim, JS Ju… - Progress in Neuro …, 2012 - Elsevier
… minocycline or SB203580 attenuated mechanical allodynia. … the effects exerted on mechanical
allodynia by minocycline, a … mirror image mechanical allodynia in our rat model. Recently, …
allodynia by minocycline, a … mirror image mechanical allodynia in our rat model. Recently, …
Local sympathectomy promotes anti-inflammatory responses and relief of paclitaxel-induced mechanical and cold allodynia in mice
… Similarly, minocycline, an antibiotic that inhibits monocyte/… pain-like behaviors by facilitating
nociceptive transmission. … and attenuation of paclitaxel-induced mechanical allodynia by …
nociceptive transmission. … and attenuation of paclitaxel-induced mechanical allodynia by …
Expression profiling of genes modulated by minocycline in a rat model of neuropathic pain
E Rojewska, M Korostynski, R Przewlocki… - … pain, 2014 - journals.sagepub.com
… on the development of mechanical allodynia and thermal … (twice daily; 30 mg/kg ip) significantly
attenuated the allodynia … the enhanced synthesis of proinflammatory cytokines. Recent …
attenuated the allodynia … the enhanced synthesis of proinflammatory cytokines. Recent …