Mapping, fine mapping, and molecular dissection of quantitative trait loci in domestic animals

M Georges - Annu. Rev. Genomics Hum. Genet., 2007 - annualreviews.org
… As a result, domestic animal populations are becoming invaluable resources for studying …
complex traits in domestic animals. As many phenotypes studied in animals are quantitative, …

Wild and domestic animals variably display Neu5Ac and Neu5Gc sialic acids

N Nemanichvili, CM Spruit, AJ Berends, A Gröne… - …, 2022 - academic.oup.com
… The C-5 position of the sialic acid can be modified to form N-acetylneuraminic … animals
investigated in this article (Table 2), of which the genomes were present in the whole-genome

[HTML][HTML] Genetic resources, genome mapping and evolutionary genomics of the pig (Sus scrofa)

K Chen, T Baxter, WM Muir, MA Groenen… - International Journal of …, 2007 - ncbi.nlm.nih.gov
Domestic animal species have experienced strong selective pressures directed at genes or
genomic … beneficial effects on a species through genome modification. It has been suggested …

The oviduct: functional genomic and proteomic approach

I Mondéjar, OS Acuna… - … in domestic animals, 2012 - Wiley Online Library
… This review examines and compares several studies related to the proteomic and transcriptomic
profile of the oviduct in different domestic animals. This information could be important …

Precise plant breeding using new genome editing techniques: opportunities, safety and regulation in the EU

F Hartung, J Schiemann - The Plant Journal, 2014 - Wiley Online Library
… , and make it possible to precisely perform genome modifications in plants. The major problem,
… used for human nutrition, feeding of domesticated animals or fibre production has been …

Differential mRNA expression and promoter methylation status of SYCP3 gene in testes of yaks and cattle‐yaks

S Wang, Z Pan, Q Zhang, Z Xie… - … in domestic animals, 2012 - Wiley Online Library
… DNA methylation is one of the major epigenetic modification forms at the genome level of
vertebrates. By influencing chromatin structure, DNA conformation, chromatin stability and the …

Farm animals are important biomedical models

DL Hamernik - Animal Frontiers, 2019 - academic.oup.com
genome sequence between cattle, pigs, and humans; and the ability to genetically modify
farm animals … to the use of farm animals compared with traditional laboratory species when …

Generation of RUNX3 knockout pigs using CRISPR/Cas9‐mediated gene targeting

JT Kang, J Ryu, B Cho, EJ Lee, YJ Yun… - … in Domestic Animals, 2016 - Wiley Online Library
… on a specific locus of genome and the RUNX3 knockout pigs … with specific genetic modification
either by modifying somatic … In this study, we introduced genetic modification in PFFs and …

Somatic cell nuclear transfer and transgenesis in large animals: current and future insights

C Galli, I Lagutina, A Perota, S Colleoni… - … in domestic animals, 2012 - Wiley Online Library
… Other powerful tools in genome modifications are represented by … In addition, modification
of the natural RRS for these … DNA sequence into a specific genomic locus that was previously ‘…

Highly efficient modification of beta-lactoglobulin (BLG) gene via zinc-finger nucleases in cattle

S Yu, J Luo, Z Song, F Ding, Y Dai, N Li - Cell research, 2011 - nature.com
… In summary, this study demonstrates that ZFNs are very efficient for gene editing of large
domestic animals as in other species. The high frequency of induced bi-allelic mutations should …