GL. 03 Molecular windows into speech and language disorders

SE Fisher - Journal of Neurology, Neurosurgery & Psychiatry, 2011 - jnnp.bmj.com
… It is emphasised that FOXP2 is not the mythical “gene for speech”, but represents one piece
of a complex puzzle. I will describe how FOXP2 can be used as a unique window into key …

Evolution of speech: Anatomy and control

B De Boer - Journal of Speech, Language, and Hearing Research, 2019 - ASHA
… This article critically reviews work on the evolution of speech in the context of motor control.
It presents a brief introduction to the field of language evolution, of which the study of the …

[引用][C] MORE THAN JUST SMALL TALK

T Fitch - SYDNEY BRENNER'S 10-ON-10: THE CHRONICLES …, 2019 - World Scientific
… of FOXP2, … FOXP2 variant allows scientists to explore when human language evolved. From
recently sequenced Denisovan and Neanderthal genomes, we learnt that the human FOXP2

Can developmental disorders reveal the component parts of the human language faculty?

M Thomas, A Karmiloff-Smith - Language learning and …, 2005 - Taylor & Francis
… Amongst these Bates identified: (a) genetic alterations that gave us better fine motor
control (like FOXP2); (b) genetic alterations that gave us better perceptual abilities; (c) genetic …

[图书][B] FoxP genes subdivide interneuron subclasses in the developing mouse spinal cord

TTH Wong - 2009 - search.proquest.com
… In order to quantify the number of V0s marked by FoxP2 at E12.5, I counted the number of
FoxP2… neurons are FoxP2+, indicating that FoxP2 marks a significant subset the V0d’s (Fig 8b) …

Asymmetry of the brain: development and implications

V Duboc, P Dufourcq, P Blader… - Annual review of …, 2015 - annualreviews.org
… for FoxP2 in promoting neuronal plasticity. In this songbird, FoxP2 expression increases
during song learning in … Furthermore, lentiviral-mediated RNAi loss of FoxP2 function results in …

What are the possible biological and genetic foundations for syntactic phenomena?

S Számadó, JR Hurford, DVM Bishop, TW Deacon… - 2009 - direct.mit.edu
… use nonhuman models to shed light on FoxP2 neural function. For example, work to detect
… with the altered motor learning exhibited by mutant mice bearing the KE-like Foxp2. Perhaps …

[HTML][HTML] Evolution at two levels: on genes and form

SB Carroll - PLoS biology, 2005 - journals.plos.org
… of vocal learning in birds. These changes could arise through the evolution of FOXP2 cis-regulatory …
, or of the regulatory or coding sequences of transcription factors that control FOXP2. …

Bates's emergentist theory and its relevance to understanding genotype/phenotype relations

A Karmiloff-Smith - Beyond nature-nurture: Essays in honor of …, 2004 - books.google.com
… Amongst these Bates points to the interaction of all of the following: (a) genetic alterations
that gave us better fine motor control (like FOXP2), (b) genetic alterations that permitted a more …

[PDF][PDF] Characterization of transcription factors in monogenic disorders of speech and language

SB Estruch - 2018 - pure.mpg.de
… in learning the necessary motor skills … motor control observed in some subjects with FOXP2
disruptions; such underlying difficulties might be particularly apparent for learning the motor