Tug of war between Acinetobacter baumannii and host immune responses

FJ Li, L Starrs, G Burgio - Pathogens and disease, 2018 - academic.oup.com
leads to activation of downstream inflammasomes to develop … post-infection in mice lacking
functional reactive oxygen … , is able to inhibit the NLRP3 inflammasome in a ‘T6SS effector E. …

Inflammasome activation in acute lung injury

MJ McVey, BE Steinberg… - … -Lung Cellular and …, 2021 - journals.physiology.org
… suppression of NLRP3 inflammasome activation by IL-4 has also … NLRP3-mediated
inflammasome signaling contributes to … , but not NLRP3 inflammasome-knockout mice, …

Nucleotide-binding oligomerization domain 1 is dispensable for host immune responses against pulmonary infection of Acinetobacter baumannii in mice

MJ Kang, JA Choi, JH Choi, AR Jang, JY Park… - Laboratory Animal …, 2018 - Springer
NLRP3 inflammasome mediates interleukin- production in immune cells in response
to Acinetobacter baumannii and contributes to pulmonary inflammation in mice. Immunology. …

Effect of Tocilizumab on Acinetobacter baumannii Lung Infection in an Immunosuppressed Rat Model

D Celebi, Z Halici, O Celebi, N Akgun… - Kafkas Üniversitesi …, 2022 - vetdergikafkas.org
… infection in immunosuppressed rats. A forty-eight female … responses which leads to the
production of proinflammatory … baumannii infections in patients with a weak immune system […

Identification of two variants of Acinetobacter baumannii strain ATCC 17978 with distinct genotypes and phenotypes

CDM Wijers, L Pham, S Menon, KL Boyd… - … and Immunity, 2021 - Am Soc Microbiol
… increased neutrophilic lung inflammation in a mouse model of … gene contributes to bacterial
resistance to cell envelope … of the NLRP3 inflammasome resulting in the production of IL-1β, …

[HTML][HTML] Inhibition of sphingosine-1-phosphate receptor 3 suppresses ATP-induced NLRP3 inflammasome activation in macrophages via TWIK2-mediated potassium …

Y Wang, C Wang, Q He, G Chen, J Yu, J Cang… - Frontiers in …, 2023 - frontiersin.org
Interleukin- (IL-1β) in the cell culture supernatant was detected … the survival and lung
vascular leakage in mice with cecal … sepsis, contributing to systemic inflammation and secondary …

Cinnamaldehyde suppresses NLRP3 derived IL-1β via activating succinate/HIF-1 in rheumatoid arthritis rats

P Liu, J Wang, W Wen, T Pan, H Chen, Y Fu… - International …, 2020 - Elsevier
… α (TNF-α) and interleukin- (IL-1β), but they also contribute to the … inflammatory mediators
released by activated immune cells … HIF-1α-mediated NLRP3 inflammasome and affects IL-1β …

… suppresses NLRP3 inflammasome activation via promoting autophagy in LPS-stimulated murine macrophages and protects against CLP-induced sepsis in mice

Y Ge, X Xu, Q Liang, Y Xu, M Huang - Inflammation Research, 2019 - Springer
… LPS-stimulated NLRP3 inflammasome activation, as well as interleukin- (IL-1β) …
Sepsis leads to the imbalance of pro-inflammatory and anti-inflammatory responses and cell-mediated

[HTML][HTML] Analysis of immune responses in Acinetobacter baumannii-infected klotho knockout mice: a mouse model of Acinetobacter baumannii infection in aged hosts

Y Sato, S Tansho-Nagakawa, T Ubagai… - Frontiers in …, 2020 - frontiersin.org
… that pulmonary inflammation was elicited in klotho KO micemediated signaling was weak
in the neutrophils of klotho KO … in inflammatory responses leads to a better outcome in acute …

Molecular mechanisms and functions of pyroptosis, inflammatory caspases and inflammasomes in infectious diseases

SM Man, R Karki, TD Kanneganti - Immunological reviews, 2017 - Wiley Online Library
… indicates that cell death contributes to immune defense against … -1 [also known as
interleukin--converting enzyme (ICE)].13 … and both the AIM2 and NLRP3 inflammasomes in …