Pyroptosis: a new regulating mechanism in cardiovascular disease

N Ji, Z Qi, Y Wang, X Yang, Z Yan, M Li… - … of inflammation …, 2021 - Taylor & Francis
NLRP3, and the structurally altered NLRP3 inflammasome … of NLRP3 leads to a concomitant
high activation of NLRP3 … Caspase-1 mediates the cleavage of interleukin- (IL-1β) …

Role of interleukin-1 in the pulmonary immune response duringPseudomonas aeruginosa pneumonia

MJ Schultz, AW Rijneveld, S Florquin… - … -Lung Cellular and …, 2002 - journals.physiology.org
… IL-1 in lung inflammation during pneumonia caused by … are elevated in lungs of mice
suffering from Pseudomonas … KC may also have contributed to the diminished neutrophil …

The Pseudomonas aeruginosa Type III secretion system exoenzyme effector ExoU induces mitochondrial damage in a murine bone marrow-derived macrophage …

KS Hardy, AN Tuckey, NA Housley… - … and Immunity, 2022 - Am Soc Microbiol
… , interleukin (IL-1β), to suppress activation of inflammation… to acknowledge possible
contributions from other cytosolic … Interestingly, the NLRP3 inflammasome has been previously …

[HTML][HTML] Antibiotics as immunomodulators: a potential pharmacologic approach for ARDS treatment

A Sauer, K Peukert, C Putensen… - European Respiratory …, 2021 - Eur Respiratory Soc
leads to influx of protein-rich pulmonary oedema fluid and … the inflammatory response is
the NLRP3 inflammasome which … -induced lung injury in mice by inhibiting inflammasome-…

Immune functions of serum amyloid A

KK Eklund, K Niemi, PT Kovanen - Critical Reviews™ in …, 2012 - dl.begellhouse.com
… through TLR4 leads to an increased production of nitric oxide … the NLRP3 inflammasome as
the inflammasome responsive to … matory response to Acinetobacter baumannii pneumonia. J …

NLRP3 knockout in mice provided protection against Serratia marcescens-induced acute pneumonia by decreasing PD-L1 and PD-1 expression in macrophages

K Chen, S Liu, J Tang, M Liu, X Chen, Z Liu… - International …, 2024 - Elsevier
… triggers NLRP3 inflammasome activation, leading to acute lung … This leads to reduced PD-L1
and PD-1 expression, especially … -mediated pyroptosis and p-MLKL-mediated necroptosis …

Quinones as preventive agents in Alzheimer's diseases: focus on NLRP3 inflammasomes

D Chen, H Gao, C Peng, S Pei, A Dai… - Journal of Pharmacy …, 2020 - academic.oup.com
… Da-bao Chen and Hua-wu Gao contributed equally to this … [4–6] Studies have shown that
elevated interleukin- (IL-1β) … in STZ induced mouse model of AD via Nrf2/ARE mediated

Transcriptional regulation of inflammasomes

M Cornut, E Bourdonnay, T Henry - International journal of molecular …, 2020 - mdpi.com
… the NLRP3 inflammasome downstream of noncanonical … Indeed, Acinetobacter baumannii
infection induces a 2–4-fold … IL-1β produced by T cells contributes to chronic inflammatory

Reactive oxygen species (ROS) scavenging biomaterials for anti-inflammatory diseases: From mechanism to therapy

J Liu, X Han, T Zhang, K Tian, Z Li, F Luo - Journal of Hematology & …, 2023 - Springer
… -1 promotes inflammation by cleaving pro-interleukin- (pro-… in ROS-mediated NLRP3
inflammasome activation, which … In particular, MAPK-mediated inflammation leads to changes …

Syntaxin17 Restores Lysosomal Function and Inhibits Pyroptosis Caused by Acinetobacter baumannii

Z An, W Ding - Journal of Microbiology, 2024 - Springer
… The Alexa Fluor 488-labled anti-rabbit or TRITC-labled anti-mousebaumannii leads to
lysosomal disorder and hinders … baumannii-mediated pyroptosis, we examined the expression of …