Expression of the adult ADHD-associated gene ADGRL3 is dysregulated by risk variants and environmental risk factors

RV McNeill, VS Palladino… - The World Journal of …, 2021 - Taylor & Francis
… Pharmacological treatment with methylphenidate (MPH) or … of ADHD heritability explained
by common genetic variants in … , n = 7 AA and n = 10 AG/GG), but this was no longer significant

High sibling correlation on methylphenidate response but no association with DAT1‐10R homozygosity in Dutch sibpairs with ADHD

EM van der Meulen, SC Bakker… - Journal of Child …, 2005 - Wiley Online Library
… ) 7-repeat alleles. This study examined the sibling correlation of methylphenidate response
… Of these children only 82 fulfilled the seven inclusion criteria and had no missing data, so …

[HTML][HTML] … of the norepinephrine transporter (Net) gene Slc6a2 is associated with clinical response to atomoxetine in attention-deficit hyperactivity disorder (ADHD)

N Ramoz, C Boni, ACM Downing, SL Close… - …, 2009 - nature.com
response was independent of the genetic variants of … of 23 candidate genes in attention
deficit hyperactivity disorder: … Response to methylphenidate in adults with ADHD is associated …

DRD4 exon 3 genotype and ADHD: Randomised pharmacodynamic investigation of treatment response to methylphenidate

D Naumova, N Grizenko, SM Sengupta… - The World Journal of …, 2017 - Taylor & Francis
candidate genes were associated with childhood ADHD, all … an association between the
7-repeat allele and poorer … to an a priori association between genetic variants in this gene and …

Further evidence of association between amphetamine response and SLC6A2 gene variants

AM Dlugos, A Hamidovic, AA Palmer, H de Wit - Psychopharmacology, 2009 - Springer
… The present findings add to a growing literature on the genetic influences on … have identified
several candidate genes that are associated with amphetamine response. For example, …

ADHD pharmacogenetics across the life cycle: new findings and perspectives

EM Bruxel, GC Akutagava‐Martins… - … of Medical Genetics …, 2014 - Wiley Online Library
… (eg, methylphenidate—MPH, amphetamines) and non-stimulants (… The majority of candidate
genes investigated in … to identify genetic variants associated with medication response or …

Attention deficit hyperactivity disorder pharmacogenetics: the dopamine transporter and D4 receptor

JJ McGough - Pharmacogenomics, 2012 - Future Medicine
methylphenidate responses in individuals homozygous with either ten-repeat or nine-repeat
alleles, increased responses with the homozygous ten-repeat, or no gene … copy of the seven-…

… (COMT) Val158Met polymorphism are associated with methylphenidate response in adolescents with attention deficit/hyperactivity disorder: a case control …

A Pekcanlar Akay, Ç Eresen Yazıcıoğlu… - Psychiatry and …, 2018 - Taylor & Francis
… studies declared at least four candidate genes that were related to ADHD (… No evidence
was found for an association between the DRD4 7-repeat allele and ADHD when our ADHD

Dopamine transporter genotype influences the physiological response to medication in ADHD

DL Gilbert, Z Wang, FR Sallee, KR Ridel, S Merhar… - Brain, 2006 - academic.oup.com
… study to measure and compare effects of two ADHD medications, methylphenidate (MPH), a
… children with ADHD. In addition, we wished to determine whether a genetic variation in the …

Attentiondeficit hyperactivity disorder: A study of association with both the dopamine transporter gene and the dopamine D4 receptor gene

T Roman, M Schmitz, G Polanczyk… - … of medical genetics, 2001 - Wiley Online Library
… An evidence of association between the DRD4 7-repeat allele and ADHD was detected …
However, it is important to stress that this is the first study evaluating candidate genes in the …