… an increase in CD8 T cell density in post treatment biopsies [79,… Oncolytic adenovirus armed
with the chemokine RANTES (… be heterogenous expression of the CAR target antigens and …

… ICAM-1 Expression of GC Cell Lines … -1 expression and as target cells for validation of
CAR T cell activity. According to the molecular subtypes by The Cancer Genome Atlas (TCGA), …

… , oncolytic adenoviruses expressing bispecific T cell engagers have shown to effectively target
… This includes the use of anti-cytotoxic T cell lymphocyte antigen 4 (CTLA4) antibodies and …

… cells (APCs) leads to T-cell response. It was reported that … clinical trials where oncolytic
adenoviruses are used either … Analysis of biopsies on days 29 and 3 months after infusion …

… this or any other protocol involving human biopsies. … Oncolytic Adenovirus Here, we describe
an experiment using an EpCAM-targeted bispecific T cell engager delivered by an oncolytic …

… Importantly, the T-cell/target cell adherence facilitated by … provide an opportunity to redirect
T-cell cytotoxicity to tumor cells. … Two recent studies engineered an oncolytic adenovirus to …

… of cytotoxic lymphocytes and activation of T cell response, … Biopsies of injected lesions were
performed in phase I and … differential display code 3) oncolytic adenovirus, showing that mK5 …

… combination with ICIs and T cell-based therapies [4]. ICIs that … -7-loaded oncolytic adenovirus
combined with B7H3-targeted CAR-… In this study, fluid biopsies were used to analyze key …

… -target … expression of bispecific (CD3 and TAA) T cell engager (BiTE) molecules from OVs.
These BiTE molecules can drive activation of cytotoxic T cells by generating an artificial, T cell …

… Center from a single fineneedle biopsy [14] conform the … the incorporation of a bispecific
T-cell engager directed at FAP [… Finally, we addressed whether the superior cytotoxicity of …