In vivo NAD assay reveals the intracellular NAD contents and redox state in healthy human brain and their age dependences

XH Zhu, M Lu, BY Lee, K Ugurbil… - Proceedings of the …, 2015 - National Acad Sciences
… in vivo NAD assay that uses the high-field MR scanner and is capable of noninvasively assessing
NAD + and NADH contents and the NAD + /NADH redox … works well in animal brains at …

[PDF][PDF] Pharmacokinetic aspects of reduced nicotinamide adenine dinucleotide (NADH) in rats

A Rex, H Fink - Front Biosci, 2008 - article.imrpress.com
… absorption of NADH in the small intestine in vitro using the … Results of animal studies suggested
beneficial effects of NADH … Due to its relevant roles in oxidation/reduction reactions and …

Multisite measurements of NADH redox state from cerebral cortex of the awake animal

A Mayevsky, B Chance - Oxygen Transport to Tissue—IV, 1983 - Springer
… We monitored NADH in vivo by using 4 light guides held in a special cannula located alX>Ve
the tv.o henispheres (Figure 5) and the brain was frozen, under unilateral occlusion, by the …

MITOCHONDRIAL FUNCTION AND TISSUE VIABILITY IN VIVO: FROM ANIMAL EXPERIMENTS TO CLINICAL APPLICATIONS. FORTY YEARS OF FRUITFUL …

A Mayevsky - Journal of Innovative Optical Health Sciences, 2011 - World Scientific
… In addition to the in-depth survey of NADH measurement in experimental animals, the present
work suggests the potential use of NADH monitoring in a medical device. This new device …

Mitochondrial redox imaging for cancer diagnostic and therapeutic studies

LZ Li, HN Xu, M Ranji, S Nioka… - Journal of innovative …, 2009 - World Scientific
… to achieve redox imaging ex vivo/in vivo with potentially more clinical applications. It may
be of … Chance, “Oxidation-reduction states of NADH in vivo: From animals to clinical use,” …

Intracellular coenzymes as natural biomarkers for metabolic activities and mitochondrial anomalies

AA Heikal - Biomarkers in medicine, 2010 - Future Medicine
… in a wide range of cellular oxidationreduction reactions. Importantly, NADH and FAD are …
our ability to precisely quantify the role of NADH and FAD in vivo in metabolic activities, and to …

FLUORESCENT IMAGES OF MITOCHONDRIAL REDOX STATES IN IN SITU MOUSE HYPOXIC ISCHEMIC INTESTINES

M Ranji, S Nioka, HN Xu, B Wu, LZ Li… - Journal of Innovative …, 2009 - World Scientific
NADH and Fp fluorescence. The aim of this study is to use the redox ratio to assess the tissue
oxidationreduction … fluorescence of NADH and NADPH of liver in vivo.They showed that …

Evaluation of the CritiView in pig model of abdominal aortic occlusion and graded hemorrhage

A Mayevsky, S Preisman, PE Willenz… - … Applications IX, 2009 - spiedigitallibrary.org
… in vivo could be done by monitoring the oxidation reduction state of the respiratory chain.
Thus, the NADH … After testing the CritiView in vitro as well as in vivo in small animals (rats and …

Real-time optical monitoring of tissue vitality in vivo

A Mayevsky, T Manor, E Pevzner… - … Applications II, 2002 - spiedigitallibrary.org
… chronic), usefulness in animal studies or in clinical situations or the level of invasiveness to
… various organs in vitro as well as in vivo. The oxidation reduction state of NADH can serve as …

Instrumentation for in vivo cerebral NADH studies in squirrel monkey

RE Anderson, TM Sundt - IEEE Transactions on Biomedical …, 1975 - ieeexplore.ieee.org
… (NADH) concentrationhas afforded an opportunity to record accurately the oxidation-reduction
Barbiturate anesthesia: Typical NADH curve before and after MCA occlusion in animal