… and NADH (7). This optical redox ratio provides relative changes in the oxidation-reduction
state … This study was approved by the institutional animal use and care committee and meets …

… In cells and tissues this excitation wavelength is much less effective than it is, for example,
for riboflavin in vitro. The reason for this is not clearly understood, but two points could be …

… vitro and in vivo in a small animal model and in preliminary … An intensive use of the in vivo
NADH monitoring approach … by monitoring of the oxidation-reduction state of cytochrome aa3 (…

… ) defined for the first time the metabolic states of isolated mitochondria in vitro, and correlated
these states to the oxidation–reduction levels of respiratory enzymes including the NADH. …

… NADH fluorescence is more commonly used for the evaluation of mitochondrial function in
the in vivo models … All the animals received humane care in accordance with the European …

… 4 where the initial NADH fraction of the signal prior to PDT is 0.16 for non… animals and 0.23
for injected animals. This increase in NADH fluorescence was observed in all animals within …

… Cellular oxidation–reduction reactions are mainly regulated … animals were approved by
the Institutional Animal Care and … To visualize NADPH and NADH dynamics in vivo, we …

… and could be monitored in vivo, using optical spectroscopy, in animal models as well as in
… “Oxidation-reduction states of NADH in vivo: From animals to clinical use”. Mitochondrion …

… Chance and his colleagues1-13 originally described the technique for in vivo recording of
NADH fluorescence as an indicator of the intracellular oxidation-reduction state. They took …

… mouse myoblasts in vitro and quadriceps of old mice ex vivo. More … + /NADH imbalance and
decreases NADH levels in vivo. … several minutes after sacrificing the animal and snap-frozen …