Mitochondrial NADH fluorescence is enhanced by complex I binding

K Blinova, RL Levine, ES Boja, GL Griffiths, ZD Shi… - Biochemistry, 2008 - ACS Publications
… ) NADH fluorescence efficiency in vitro. However, the relative contribution of these and
potentially other NADH binding sites to the overall mitochondrial NADH … in the Animal Care and …

Real Time In Vivo Evaluation of Mitochondrial Activity and Brain Functions during Ischemic Stroke

A Mayevsky - Medical Research Archives, 2023 - esmed.org
… of NADH could be achieved in vivo by exposing the animal to anoxia (100% nitrogen), the
minimal level that could be monitored in vivo is … on the oxidation reduction state of NADH was …

Spatial characterization of bioenergetics and metabolism of primordial to preovulatory follicles in whole ex vivo murine ovary

R Cinco, MA Digman, E Gratton… - Biology of …, 2016 - academic.oup.com
… free/bound NADH axis; N = 22 follicles across nine animals. D) … free/bound NADH ratios in
freshly dissected whole, ex vivo … the ex vivo environment differs from the in vivo environment, …

Optical redox ratio differentiates breast cancer cell lines based on estrogen receptor status

JH Ostrander, CM McMahon, S Lem, SR Millon… - Cancer research, 2010 - AACR
oxidation-reduction (redox) ratio is a measure of cellular metabolism and can be determined
by the ratio of NADH/… be recapitulated in mouse models in vivo. We have already begun to …

3D imaging of the mitochondrial redox state of rat hearts under normal and fasting conditions

HN Xu, R Zhou, L Moon, M Feng… - Journal of innovative …, 2014 - World Scientific
… In this study, we observed local heterogeneities of NADH, Fp and NADH/Fp ratio in both
the … Chance, \Oxidation-reduction states of NADH in vivo: From animals to clinical use," …

Cerebral oxidative metabolism and redox state during hypoxia-ischemia and early recovery in immature rats

JY Yager, RM Brucklacher… - American Journal of …, 1991 - journals.physiology.org
… and mitochondrial oxidation-reduction (redox) states of cerebral … Cytoplasmic and mitochondrial
redox (NAD+/NADH) states … hypoxic and hypoglycemic conditions in vitro. J. Neurochem. …

In vivo multiphoton microscopy detects longitudinal metabolic changes associated with delayed skin wound healing

JD Jones, HE Ramser, AE Woessner… - Communications …, 2018 - nature.com
… These cofactors undergo oxidation/reduction reactions during … The goal of this study was
to establish whether NADH and FAD … in live animals over multiple days. The successful …

Catalytic oxidation and reduction reactions of hydrophilic carbon clusters with NADH and cytochrome C: features of an electron transport nanozyme

PJ Derry, LG Nilewski, WKA Sikkema, K Mendoza… - Nanoscale, 2019 - pubs.rsc.org
… we tested in vitro their potential therapeutic application as an … or the E 1/2 of the
oxidationreduction cycle, of +11 mV and ∼… Early large animal in vivo experiments by Eddy …

HYPERBARIC HYPEROXIA AND THE BRAIN IN VIVO: THE BALANCE BETWEEN THERAPY AND TOXICITY

J Sonn, E Meirovithz, A Mayevsky - Journal of Innovative Optical …, 2008 - World Scientific
… and Chance, B., “Oxidation-reduction states of NADH in vivo: From animals to clinical use,”
Mitochondrion 7, 330–339 (2007). 3. Gill, AL and Bell, CN, “Hyperbaric oxygen: Its …

Microscopic analysis of NADH fluorescence during aerobic and anaerobic liver preservation conditions: a noninvasive technique for assessment of hepatic …

H Klauke, T Minor, B Vollmar, W Isselhard, MD Menger - Cryobiology, 1998 - Elsevier
… of hepatic tissue NADH has further been proven to reliably reflect hepatic energy status in
terms of tissue oxygenation and liver function in an in vivo animal model of hemorraghic shock …