… survival by activating PI3K/AKT signaling. … maintains the stemness of cancer stem cells through
AKT signaling. We therefore sought to … apoptosis by maintaining AKT phosphorylation. (A) …

… , where it is thought to function in maintaining stem cell … in the expression of proteins involved
in the PI3K/AKT pathway; … evidence of the participation of PD-L1 in the activity of CSCs. It is …

… the PD-L1 expression and controlling PTEN/PI3K/AKT/mTOR. … we evaluated PD-L1 transcript
and protein expression levels … of c-Myc in sustaining the proliferation and chemoresistant …

… Maintaining the balance between eliciting immune responses … PTEN which terminates the
PI3K-AKT-PKCθ pathway and … by inducing expression of HLA-G, PD-L1 as well as promoting …

… Additionally, PD-L1 was shown to promote stemness in breast cancer by increasing the
expression of stemness factors OCT4 and Nanog by sustained PI3K/Akt pathway activation [60]. …

… -150 and promoted the expression of these genes to sustained … via EP4/PI3K/AKT/NOTCH/WNT
pathway. In addition, Aberrantly … Studies showed that PD-L1 expression was positively …

… PD-L1 was revealed to play an important role in sustaining the stemness of breast cancer
cells by activating the PI3K/AKT … - 96 CAFs also promote EMT transformation by activating TGF-…

… PD-L1 promotes cancer stem-like cells by maintaining the PI3K/AKT pathway and their
downstream stem-related embryonic antigens OCT4 and Nanog [20]. Indeed, MPBCs were found …

… PD-1 and PD-L1 enhances the T-cell response and mediates … has been shown crucial to
maintaining homeostasis of the … the PI3K/Akt pathway regulates PD-L1 expression by either …

… of PD-L1, which strengthened PD-L1 expression and promoted … breast EMT by activating
PI3K/Akt pathway and that PD-L1 … PD-L1 is considered essential in maintaining the stemness …