Pathomechanisms of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious environment

J Riegger, RE Brenner - International journal of molecular sciences, 2020 - mdpi.com
… development of so-called posttraumatic osteoarthritis (PTOA). … pathomechanisms of PTOA
and in particular the behavior and fate of the surviving chondrocytes, comprising chondrocyte

[图书][B] Modeling the Post-injury Joint Environment for the Investigation of Post-traumatic Osteoarthritis

S Ayala - 2022 - search.proquest.com
… used to spatially map chondrocyte behavior in Gnee and anGle cartilage … Pathomechanisms
of posttraumatic osteoarthritis: Chondrocyte behavior and fate in a precarious environment

[图书][B] … the Structural and Functional Consequences of Traumatic Joint Injury and Their Relation to NF-κB in a Non-invasive Model of Post-traumatic Osteoarthritis

IM Berke - 2020 - search.proquest.com
behavior and cartilage pathology in a non-invasive loading model of post-traumatic osteoarthritis
… inhibitor in a non-invasive loading model of post-traumatic osteoarthritis (Chapter 3) ......…

Functional duality of chondrocyte hypertrophy and biomedical application trends in osteoarthritis

S Park, A Bello, Y Arai, J Ahn, D Kim, KY Cha, I Baek… - Pharmaceutics, 2021 - mdpi.com
… Therefore, in the next section, three-dimensional environments for the advancement of
drug delivery systems and prevention of chondrocyte hypertrophy will be discussed. …

[HTML][HTML] Molecular mechanisms and potential applications of chondroitin sulphate in managing post-traumatic osteoarthritis

I Golovach, D Rekalov, Y Akimov, H Kostenko… - …, 2023 - ncbi.nlm.nih.gov
Pathomechanisms of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious
environment. Int J Mol Sci 2020; 21: 1560, DOI: 10.3390/ijms21051560. [PMC free article…

Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models

C He, KL Clark, J Tan, H Zhou, RS Tuan, H Lin… - Stem Cell Research & …, 2022 - Springer
… degeneration, as in post-traumatic osteoarthritis (PTOA). … gelatin and promoting chondrogenic
differentiation for 28 days in … in providing a viscoelastic environment suitable for promoting …

Microenvironment in subchondral bone: predominant regulator for the treatment of osteoarthritis

W Hu, Y Chen, C Dou, S Dong - Annals of the Rheumatic Diseases, 2021 - ard.bmj.com
Osteoarthritis (OA) is a degenerative joint disease in the elderly. Although OA has been
considered as primarily a disease of the articular cartilage, the participation of subchondral bone …

TKA for posttraumatic osteoarthritis is more complex and needs more surgical resources

J Dexel, F Beyer, C Lützner, C Kleber, J Lützner - Orthopedics, 2016 - journals.healio.com
… The purpose of this study was to evaluate the surgical effort of total knee arthroplasty (TKA)
for posttraumatic osteoarthritis (PTOA) compared with primary osteoarthritis (OA). A total of …

Mechanical and Biologic Impact of Dynamic Loading on Bovine and Human Models of Osteoarthritis

HJ Szapary - 2022 - dspace.mit.edu
osteoarthritis (OA), a disease characterized by cartilage degradation. Additionally, dynamic
loading has been demonstrated to affect chondrocyte … preventing post-traumatic osteoarthritis

Evaluation of the Regenerative Potential of Osteoarthritic Chondrocytes for Cartilage Tissue Engineering

C Davis - 2023 - deepblue.lib.umich.edu
… enzymes that often lead to post-traumatic osteoarthritis (PTOA). These pathways promote
phenotypic changes characteristic of chondrocyte hypertrophy and senescence1. Senescence …