p53-induced GDF-15 expression promotes a pro-regenerative response in human chondrocytes upon cartilage injury

SS Marques, A Liebaug, S Maurer, D Rothenbacher… - bioRxiv, 2024 - biorxiv.org
Post-traumatic osteoarthritis: the worst associated injuries and … Pathomechanisms of
Posttraumatic Osteoarthritis: Chondrocyte Behavior and Fate in a Precarious Environment. Int J Mol …

miR-140-5p protects cartilage progenitor/stem cells from fate changes in knee osteoarthritis

Y Chen, H Huang, W Zhong, L Li, Y Lu, H Si - International …, 2023 - Elsevier
… -derived total chondrocytes while decreased in the advanced OA group. Significant fate changes
(… Although dysregulated behavior and fate such as decreased proliferation, senescence-…

Modeling early changes associated with cartilage trauma using human-cell-laden hydrogel cartilage models

C He, KL Clark, J Tan, H Zhou, RS Tuan, H Lin… - Stem Cell Research & …, 2022 - Springer
… degeneration, as in post-traumatic osteoarthritis (PTOA). … gelatin and promoting chondrogenic
differentiation for 28 days in … in providing a viscoelastic environment suitable for promoting …

[HTML][HTML] Molecular mechanisms and potential applications of chondroitin sulphate in managing post-traumatic osteoarthritis

I Golovach, D Rekalov, Y Akimov, H Kostenko… - …, 2023 - ncbi.nlm.nih.gov
Pathomechanisms of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious
environment. Int J Mol Sci 2020; 21: 1560, DOI: 10.3390/ijms21051560. [PMC free article…

Articular Cartilage—From Basic Science Structural Imaging to Non-Invasive Clinical Quantitative Molecular Functional Information for AI Classification and Prediction

B Kurz, T Lange, M Voelker, ML Hart… - International Journal of …, 2023 - mdpi.com
… diseases such as primary or post-traumatic osteoarthritis (OA/PTOA… Therefore, the mechanical
environment of chondrocytes is … aspects of the many OA pathomechanisms [56], which are …

Functional duality of chondrocyte hypertrophy and biomedical application trends in osteoarthritis

S Park, A Bello, Y Arai, J Ahn, D Kim, KY Cha, I Baek… - Pharmaceutics, 2021 - mdpi.com
… Therefore, in the next section, three-dimensional environments for the advancement of
drug delivery systems and prevention of chondrocyte hypertrophy will be discussed. …

Toll-like receptor 3 activation promotes joint degeneration in osteoarthritis

J Stolberg-Stolberg, A Boettcher, M Sambale… - Cell Death & …, 2022 - nature.com
… image uptake in chondrocytes and full-thickness cartilage. The production of IFNβ in chondrocytes
after stimulation … Chondrocyte apoptosis was chemically induced using staurosporine. …

YY1/miR-140-5p/Jagged1/Notch axis mediates cartilage progenitor/stem cells fate reprogramming in knee osteoarthritis

Y Chen, G Liao, T Ma, L Li, J Yang, B Shen… - International …, 2023 - Elsevier
… Our recent research confirmed the disordered behavior and fate in OA … Pathomechanisms
of posttraumatic osteoarthritis: chondrocyte behavior and fate in a precarious environment

In vitro characterization of doxorubicin-mediated stress-induced premature senescence in human chondrocytes

V Kirsch, JM Ramge, A Schoppa, A Ignatius, J Riegger - Cells, 2022 - mdpi.com
chondrocytes is thought to drive inflammatory processes and subsequent cartilage degeneration
in age-related as well as posttraumatic osteoarthritis (OA). … by a dysfunctional behavior, …

Visualization analysis of traumatic osteoarthritis research hotspots and content based on CiteSpace

W Ren, Y Liao - Chinese Journal of Tissue Engineering Research, 2021 - cjter.com
… RESULTS AND CONCLUSION: (1) The research of post-traumatic osteoarthritis has … of
post-traumatic osteoarthritis mainly include anterior cruciate ligament injury, chondrocytes, and …