… low-pH environment containing lysosomal … chondrocyte In comparison with the more direct
blood supply of other tissues, the rather long supply line of cartilage is much more precarious …

… Deregulation of the kinase activity by mutating the enzyme or the phosphorylation sites of
substrates causes developmental disorders and susceptibility to adverse environmental …

Oxidative stress has been implicated in the pathophysiology of myocardial failure. We tested
the hypothesis that oxidative stress can regulate extracellular matrix in cardiac fibroblasts. …

… target for the treatment of osteoarthritis. Herein, we summarize the knowledge about the
role of mast cells in the pathogenesis of osteoarthritis and outline various approaches that, to …

… The crosstalk of NF-κB with other signaling pathways is therefore critical for cellular fate,
notably survival or cell death under oxidative conditions, and will also be reviewed. …

… of the effects of Curcuma longa on osteoarthritis. For this review they will … Pathomechanisms
of Posttraumatic Osteoarthritis: Chondrocyte Behavior and Fate in a Precarious Environment…

… a high genetic predisposition to the development of post-traumatic gonarthrosis is diagnosed.
… Rhon DI, Perez KG, Eskridge SL Risk of post‐traumatic knee osteoarthritis after knee injury …

… osteoarthritis, perspectives for post-traumatic osteoarthritis: … post-traumatic osteoarthritis:
Report from an international expert working group on considerations for the design and conduct …

A osteoartrite (OA) é uma desordem articular caracterizada por inflamação crônica, degenerativa
e irreversível que conduz à dor e incapacidade. Os medicamentos padrões não são …

… However, the marketing of their products is often precarious, depending almost exclusively
on open markets. With the covid-19 pandemic many open markets were canceled in order to …