Precision medicine in diabetes prevention, classification and management

F Xie, JCN Chan, RCW Ma - Journal of diabetes investigation, 2018 - Wiley Online Library
… –renal disease and premature death than their peers with late-onset diabetes72, 73. …
Although pharmacogenetic variants might provide new perspectives on precision medicine, …

[HTML][HTML] Current research and new perspectives of telemedicine in chronic heart failure: narrative review and points of interest for the clinician

E Andrès, S Talha, AA Zulfiqar, M Hajjam… - … of Clinical Medicine, 2018 - mdpi.com
… and re-hospitalization (“personalized medicine”). In this context, MyPredi TM automatically
generates indicators of a worsening of the patient’s HF status (“predictive medicine”) [33,43]. …

[HTML][HTML] Polygenic risk scores in the clinic: new perspectives needed on familiar ethical issues

ACF Lewis, RC Green - Genome Medicine, 2021 - Springer
… The concept of a disease It is part of the hope of precision medicine that disease classification
is refined. In this vision, the broad definitions we have of conditions, based on symptoms …

[HTML][HTML] The Warburg effect in diabetic kidney disease

G Zhang, M Darshi, K Sharma - Seminars in nephrology, 2018 - Elsevier
… biology tools have shed new insights in our understanding of … pave the path for personalized
kidney precision medicine. … ultimately reach end-stage renal disease, there must be …

Healthcare in the UK–predictive, preventive and personalised medicine perspective at the beginning of the twenty-first century

K Grosios, PB Gahan, J Burbidge - … Overview: New Perspectives, 2012 - Springer
… diabetes and cardiovascular disease. In the UK approximately 16% of total NHS expenditure
is dedicated to dealing with coronary heart disease, cancer, renal disease, mental health …

Exploring the genetic basis of early-onset chronic kidney disease

A Vivante, F Hildebrandt - Nature Reviews Nephrology, 2016 - nature.com
… the most common diagnostic groups of renal disease that … genetic diagnosis, generate new
insights into disease mechanisms… through the delivery of personalized medicine; the ability to …

Osteoarthritis: new insights. Part 2: treatment approaches

DT Felson, RC Lawrence, MC Hochberg… - … of internal medicine, 2000 - acpjournals.org
… Risk factors for reversible renal failure in patients with intrinsic renal disease who are
treated with NSAIDs include age 65 years or older, hypertension or congestive heart …

Whole-exome sequencing study identifies four novel gene loci associated with diabetic kidney disease

, … Trans-Omics for Precision Medicine  … - Human molecular …, 2023 - academic.oup.com
Renal Insufficiency Cohort and Atherosclerosis Risk in Communities studies (stage 1) and
11 487 multi-ancestry Trans-Omics for Precision Medicine … findings provide new insights into …

Precision medicine in diabetes: a consensus report from the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD)

WK Chung, K Erion, JC Florez, AT Hattersley… - Diabetes …, 2020 - Am Diabetes Assoc
… of new insights into the phenotype known as “diabetes.” Increased knowledge of this condition
… at risk for reduced life span, amputation, kidney failure, and blindness. A more precise …

New insights into the immunopathogenesis of systemic lupus erythematosus

GC Tsokos, MS Lo, PC Reis, KE Sullivan - Nature Reviews …, 2016 - nature.com
… cardiovascular disease, and renal failure constitute a substantial burden, and medical costs
… In this Review, we cover new insights that extend this model and offer the potential for novel …