Sex-related differences in pharmacokinetics and pharmacodynamics of frequently prescribed drugs: a review of the literature

A Farkouh, T Riedl, R Gottardi, M Czejka… - Advances in …, 2020 - Springer
… in men and women [4]. Importantly, there are also significant differences between men and
women in … In contrast, women benefit more from opioids that interact with the κ-receptor, eg …

The current state of knowledge on age, sex, and their interactions on clinical pharmacology

JB Schwartz - Clinical Pharmacology & Therapeutics, 2007 - Wiley Online Library
… , pharmacokinetic or pharmacodynamic differences between … of older women enrolled in
premarketing pharmacokinetic or … of improved therapy through pharmacogenomic-based drug …

Gender differences in drug responses

F Franconi, S Brunelleschi, L Steardo… - Pharmacological research, 2007 - Elsevier
… Since sex is a fundamental biological variable that cannot be … and pharmacogenetics.
Moreover, this article gives a quick … Traditional risk factors differ between men and women. …

Gender differences in pharmacokinetics

CH Gleiter, U Gundert-Remy - … of drug metabolism and pharmacokinetics, 1996 - Springer
… of examples showing pharmacokinetic differences between gender. From … women compared
to men. CYP isoenzymes other than CYP 3A4 seem to be more active in men than in woman

A GENS-based approach to cardiovascular pharmacology: impact on metabolism, pharmacokinetics and pharmacodynamics

F Franconi, C Carru, I Spoletini, W Malorni… - Therapeutic …, 2011 - Future Science
… are a function of the interaction between biology and environment. … differences between
women and men that affect drug bioavailability, pharmacokinetics and pharmacodynamics. …

“Bridging the gap” everything that could have been avoided if we had applied gender medicine, pharmacogenetics and personalized medicine in the gender-omics …

D Gemmati, K Varani, B Bramanti, R Piva… - International Journal of …, 2019 - mdpi.com
… , and environmental factors mutually interact in defining sex/gender differences, and at the
… may strongly differ between males and females. While sex refers to biological and genetic …

[PDF][PDF] Pharmacokinetics, pharmacodynamics, and pharmacogenomics

SW Lam - Lancet Infect Dis, 2014 - accp.com
… physical incompatibilities that limit bioavailability. In critically ill … In general, many drug-nutrient
interactions can be circum… depend on the interaction between physiologic derangements …

Pharmacogenomics: recent progress, sex gender differences, translation into clinical practice, application in pediatrics and future perspectives

M Smolic, I Bozic, T Omanovic, L Kuna… - Southeastern …, 2017 - seemedj.mefos.unios.hr
pharmacokinetic differences between men and women are more extensive compared with
variations in pharmacodynamics (… is a rapidly emerging and promising scientific field in which …

The role of gender pharmacogenetics in the personalization of drug treatment

E Cecchin, B Posocco, S Mezzalira… - Journal of …, 2023 - ASPET
… on the interaction between gender and pharmacogenetics in … Network for Drug Safety, and
additional scientific consortia are … The most striking difference between males and females is …

[HTML][HTML] The pharmacodynamics of antipsychotic drugs in women and men

MV Seeman - Frontiers in psychiatry, 2021 - frontiersin.org
… of differences in pharmacokinetics and pharmacodynamics, clinically relevant adverse drug
reactions differ between men and women (… suggests that the biology of sex and the impact of …