Maternal diabetes causes coordinated down-regulation of genes involved with lipid metabolism in the murine fetal heart

MLS Lindegaard, LB Nielsen - Metabolism, 2008 - Elsevier
… -metabolizing genes (including lipoprotein lipase and fatty … The results suggest that maternal
type 1 diabetes mellitus in … heart triglyceride stores were not affected by maternal diabetes

Placental fatty acid transport in maternal obesity

I Cetin, F Parisi, C Berti, C Mandò… - Journal of developmental …, 2012 - cambridge.org
placental lipoprotein lipase (LPL) activity has been found to be increased by 39% in Type
1 Diabetes … in cellular triglyceride content in placentas of obese–diabetic women but not in …

Dyslipidemia, insulin resistance, and impairment of placental metabolism in the offspring of obese mothers

M Bucher, KRC Montaniel, L Myatt… - … origins of health and …, 2021 - cambridge.org
… -c) and triglycerides in fasting maternal and cord blood plasma. … explained by the placental
accumulation of ceramides and … Placental lipoprotein lipase DNA methylation levels are …

A short periconceptional exposure to maternal type-1 diabetes is sufficient to disrupt the feto-placental phenotype in a rabbit model

D Rousseau-Ralliard, A Couturier-Tarrade… - Molecular and cellular …, 2019 - Elsevier
… to increase maternal plasma triglyceride and glucose concentrations, delaying blastocyst
development associated and impairing intracellular accumulation … Analyses of gene expression

Dysregulation of placental lipid hydrolysis by high-fat/high-cholesterol feeding and gestational diabetes mellitus in mice

KB Kuentzel, I Bradić, ZN Mihalič, M Korbelius… - International Journal of …, 2022 - mdpi.com
… a consequence of the increased storage of triacylglycerol (TG). … Increased acid TG lipase
activity observed in the present … pancreatic β-cells and resemble type 1 diabetes [44]. However, …

Lipoprotein lipase and lipid profiles in plasma and placenta from normal pregnancies compared with patients with intrahepatic cholestasis of pregnancy

ZM Hao, YF Ye, YK Zhang, SF Yang, XL Ye - European Journal of …, 2016 - Elsevier
Placental triglyceride and total cholesterol levels were also … RCT activity and accumulation
of placental and plasma total … and mRNA expression in ICP placenta compared with normal …

Effect of maternal obesity and gestational diabetes on placental fatty acid uptake, metabolism and transfer to the fetus

MT Segura Moreno - 2019 - digibug.ugr.es
… levels of triglycerides and cholesterol increase in maternal blood. … lipid deposition, promoting
accumulation of maternal fat stores as … the only active lipase in the placenta. Since LPL is a …

Lipid metabolism during pregnancy and its implications for fetal growth

E Herrera, H Ortega-Senovilla - Current pharmaceutical …, 2014 - ingentaconnect.com
… Indeed, a dysregulation of placental endothelial lipase and LPL, … and placentas from women
with either type 1 diabetes or … triglyceride by human placental cells: the role of lipoprotein …

Early life exposure to fructose alters maternal, fetal and neonatal hepatic gene expression and leads to sex-dependent changes in lipid metabolism in rat offspring

ZE Clayton, MH Vickers, A Bernal, C Yap, DM Sloboda - Plos one, 2015 - journals.plos.org
… specific changes in fetal, placental and neonatal outcomes. … Maternal plasma lipase was
decreased in FR mothers at E21 (p … increased in maternal liver triglyceride content in FR mothers

Effect of type 2 diabetes mellitus on placental expression and activity of nutrient transporters and their association with birth weight and neonatal adiposity

M Castillo-Castrejon, K Yamaguchi, RL Rodel… - Molecular and cellular …, 2021 - Elsevier
… Total radiotracer accumulation within the vesicles was … glucose, maternal concentration of
lipids specifically triglycerides and … placental morphology have been described in GDM, Type 1