… of known domains within specific taxonomical groups (eg the polo boxes of PLKs). … are
indicted in the grey boxes above the heat map (CR – conserved region; Crypt. – cryptic …

… We thank the IGC imaging unit for help with image acquisition, S. … Autophosphorylation of
polo-like kinase 4 and its role in … plk4 cryptic polo box reveals two tandem polo boxes required …

… identified Polo-like kinase 4 (Plk4) (also known as Sak, Snk/Plk-… , containing only one Polo
box domain and three PEST … , including the bases of intestinal crypts. Northern blot analysis …

… Sak and Plk are protein kinases of the polo family. In lower … damaged cells, and the evolution
of cells to malignancy (… of a single polo box domain (see Figure 1.2, previous page). A …

… from an evolutionary point of view. Direct … new copy to explore mutational space, which
may opportunistically give rise to novel functions (represented by the white stripes in the box…

… In addition, I show that conductin binds to polo like kinase 1 (… the clonal evolution model
and is in line with the concept that … Subsequently, PLKs have been found in many eukaryotes …

… the first to describe and implement a concept of a stem cell as a … a polo-box domain (PBD)
which is a unique feature of the Plk … that our bodies developed evolutionary to silence the alien …

… Nevertheless, a full molecular view of centriolar assembly is … region that binds to the cryptic
polo-box (CPB) domain of ZYG… pathway in animals during evolution to coordinate centriole …

… The Polo-like kinases (PLKs) are a family of serine/threonine kinases that play a critical
role … region contains a single Polo-box and a central domain called the “cryptic Polo-box” (CPB). …