Characterizing Hematological and Reproductive Phenotypes in the Plk4+/–Mouse

BC LaBute - 2022 - search.proquest.com
… It was always great to go out to lunch, have a coffee or just hang out in the office. Than2s for
… it was originally thought to contain a single polo box, however it has been found to … Page 47 …

[HTML][HTML] Forkhead box M1 transcriptional factor is required for smooth muscle cells during embryonic development of blood vessels and esophagus

V Ustiyan, IC Wang, X Ren, Y Zhang, J Snyder… - Developmental …, 2009 - Elsevier
The forkhead box m1 (Foxm1 or Foxm1b) transcription factor (previously called HFH-11B,
Trident, Win, or MPP2) is expressed in a variety of tissues during embryogenesis, including …

Progress and renewal in gustation: new insights into taste bud development

LA Barlow - Development, 2015 - journals.biologists.com
… many plants and animals have evolved to produce bitter-tasting … We now have a clearer
image of the steps involved in taste … taste loss and permanent taste dysfunction (Box 1). In mice, …

The role of plasma membrane sodium/hydrogen exchangers in gastrointestinal functions: proliferation and differentiation, fluid/electrolyte transport and barrier integrity

K Nikolovska, UE Seidler, C Stock - Frontiers in Physiology, 2022 - frontiersin.org
… one group out of the most evolutionary conserved transport … full thickness small intestinal
crypt-villus or colonic crypt-surface cell … allows a closer look at the activity and function of certain …

[图书][B] Developmental regulation of Hand1 via nucleolar sequestration

DMJ Martindill - 2008 - search.proquest.com
… Moreover, the polo-like kinase Plk4 (Sak) is responsible for this … divergence of Plk4 from
other members of the Plk family ------ … have acquired further functions during the evolution of the …

Dissecting the Rules Underlying de Novo Centrosome Biogenesis

CAAP Nabais - 2018 - search.proquest.com
… domain PB - Polo boxes PBD - Polo box domain PCL - … Plk4, the odd one out in the Plk
family ………………..69 1.3.2 … and organisms, from an evolutionary point of view, one can …

Molecular mechanisms of colorectal carcinogenesis

J Roper, KE Hung - Molecular Pathogenesis of Colorectal Cancer, 2013 - Springer
Polo-like kinases (Plk) are serine/threonine kinases, which … Fbxw7/hCdc4 is a member of the
F-box family of proteins, … contrast to SSAs in which new crypts are generally anchored to the …

[PDF][PDF] Targeting Oncogenic Transcription Factors in Alveolar Rhabdomyosarcoma

V Thalhammer - 2015 - zora.uzh.ch
… The polo-‐box binding domain is responsible for binding of interaction partners primed …
Available inhibitors are either targeting the ATP binding site or the polo-‐box binding domain and …

Spindle orientation, asymmetric division and tumour suppression in Drosophila stem cells

C Gonzalez - Nature Reviews Genetics, 2007 - nature.com
… Given the striking degree of evolutionary conservation of the general … For instance, each
crypt in the human colon is thought to … organs (Box 2). Moreover, and complying further with the …

[图书][B] Medieval death: ritual and representation

P Binski - 1996 - books.google.com
… shrines in discrete places like crypts or in spaces accessible to, but … of prison, namely Purgatory,
evolved. No one (we assume) … of the Death of a Miser (PL. 1) elaborates in single framed …